Q9BVS4 | RIOK2_HUMAN | Serine/threonine-protein kinase RIO2 (RIOK2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01163 | RIO1 - RIO domain | 108~279 | |
| PF09202 | Rio2_N - Rio2, N-terminal | 9~91 |
3D structures mapped by conservation among orthologs
[ Domain: "winged" // Rio2_N ]
[ Domain: "Protein kinase" // RIO1 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4858983 |  |
IC50 | = | 130.0 | nM | 338.39 | CN(C)c1ccc(/N=N/c2ccccn2)c(O)c1.CS(=O)(=O)O | Homo sapiens | CHEMBL4825563 | cell-based format |
| CHEMBL5172767 |  |
IC50 | = | 139.0 | nM | 521.5 | COc1ccc(-c2ccc3[nH]c(=O)c4nnn(-c5ccc(N6CCNCC6)c(C(F)(F)F)c5)c4c3c2)cn1 | Homo sapiens | CHEMBL5167390 | assay format |