Q9BPX1 | DHB14_HUMAN | 17-beta-hydroxysteroid dehydrogenase 14 (HSD17B14)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF13561 | adh_short_C2 - Enoyl-(Acyl carrier protein) reductase | 19~249 |
3D structures mapped by conservation among orthologs
[ Domain: "NAD(P)-binding Rossmann-fold domains" // adh_short_C2 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4175585 |  |
Ki | = | 1.5 | nM | 325.31 | C=C(c1ccc(F)c(O)c1)c1cccc(-c2cccc(O)c2F)n1 | Homo sapiens | CHEMBL4155465 | assay format |
| CHEMBL4165659 |  |
Ki | = | 6.0 | nM | 266.27 | O=C(c1ccc(F)c(O)c1)c1ccc2ccccc2c1 | Homo sapiens | CHEMBL4155465 | assay format |
| CHEMBL4176263 |  |
Ki | = | 6.0 | nM | 281.29 | Cc1ccc2nc(C(=O)c3ccc(F)c(O)c3)ccc2c1 | Homo sapiens | CHEMBL4155465 | assay format |
| CHEMBL4164239 |  |
Ki | = | 6.0 | nM | 373.38 | Cc1cc(-c2ccc3ccc(C(=O)c4ccc(F)c(O)c4)nc3c2)ccc1O | Homo sapiens | CHEMBL4155465 | assay format |
| CHEMBL3827618 |  |
Ki | = | 7.0 | nM | 325.3 | O=C(c1ccc(F)c(O)c1)c1cccc(-c2ccc(O)c(O)c2)n1 | Homo sapiens | CHEMBL3830811 | single protein format |
| CHEMBL3965905 |  |
Ki | = | 7.0 | nM | 309.3 | O=C(c1ccc(F)c(O)c1)c1cccc(-c2cccc(O)c2)n1 | Homo sapiens | CHEMBL3861918 | assay format |
| CHEMBL3894507 |  |
Ki | = | 7.0 | nM | 336.37 | CN(C)c1cccc(-c2cccc(C(=O)c3ccc(F)c(O)c3)n2)c1 | Homo sapiens | CHEMBL3861918 | assay format |
| CHEMBL3941236 |  |
Ki | = | 9.0 | nM | 345.28 | O=C(c1cccc(-c2cccc(O)c2F)n1)c1ccc(F)c(O)c1F | Homo sapiens | CHEMBL3861918 | assay format |
| CHEMBL4168004 |  |
Ki | = | 9.0 | nM | 292.27 | N#Cc1ccc2ccc(C(=O)c3ccc(F)c(O)c3)nc2c1 | Homo sapiens | CHEMBL4155465 | assay format |
| CHEMBL3932068 |  |
Ki | = | 9.0 | nM | 429.45 | Cc1cc(-c2ccc(C(=O)c3ccc(F)c(O)c3)nc2-c2ccc(O)c(C)c2)ccc1O | Homo sapiens | CHEMBL3861918 | assay format |
| CHEMBL4172463 |  |
Ki | = | 10.0 | nM | 335.3 | O=C(c1ccc(F)c(O)c1)c1ccc2ccc(-c3nnn[nH]3)cc2n1 | Homo sapiens | CHEMBL4155465 | assay format |
| CHEMBL3913249 |  |
Ki | = | 11.0 | nM | 343.29 | O=C(c1cccc(-c2cccc(O)c2F)n1)c1ccc(F)c(O)c1O | Homo sapiens | CHEMBL3861918 | assay format |
| CHEMBL4171902 |  |
Ki | = | 12.0 | nM | 267.26 | O=C(c1ccc(F)c(O)c1)c1ccc2ccccc2n1 | Homo sapiens | CHEMBL4155465 | assay format |
| CHEMBL3949996 |  |
Ki | = | 13.0 | nM | 327.29 | O=C(c1ccc(F)c(O)c1)c1cccc(-c2cccc(O)c2F)n1 | Homo sapiens | CHEMBL3861918 | assay format |
| CHEMBL3938843 |  |
Ki | = | 15.0 | nM | 433.41 | Cc1cc(-c2nc(C(=O)c3ccc(F)c(O)c3)ccc2-c2cccc(O)c2F)ccc1O | Homo sapiens | CHEMBL3861918 | assay format |
| CHEMBL3911402 |  |
Ki | = | 17.0 | nM | 327.29 | O=C(c1ccc(F)c(O)c1)c1ccc(-c2ccc(O)c(F)c2)cn1 | Homo sapiens | CHEMBL3861918 | assay format |
| CHEMBL3923116 |  |
Ki | = | 21.0 | nM | 324.31 | O=C(c1cccc(-c2cccc(O)c2F)c1)c1cccc(O)c1O | Homo sapiens | CHEMBL3861918 | assay format |
| CHEMBL4174579 |  |
Ki | = | 23.0 | nM | 340.31 | O=C(O)CNc1ccc2ccc(C(=O)c3ccc(F)c(O)c3)nc2c1 | Homo sapiens | CHEMBL4155465 | assay format |
| CHEMBL1928186 |  |
Ki | = | 24.0 | nM | 323.32 | Cc1cc(-c2ccc(C(=O)c3ccc(F)c(O)c3)nc2)ccc1O | Homo sapiens | CHEMBL3861918 | assay format |
| CHEMBL1928172 |  |
Ki | = | 26.0 | nM | 323.32 | Cc1cc(-c2cccc(C(=O)c3ccc(F)c(O)c3)n2)ccc1O | Homo sapiens | CHEMBL3861918 | assay format |