Q99788 | CML1_HUMAN | Chemerin-like receptor 1 (CMKLR1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 - 7 transmembrane receptor (rhodopsin family) | 57~316 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3964891 |  |
IC50 | <= | 30.0 | nM | 591.54 | Cc1cccc(C)c1N1C[C@@](CN2CCC(F)(F)CC2)(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](C)C1=O | Homo sapiens | CHEMBL3880333 | cell-based format |
| CHEMBL3898515 |  |
IC50 | <= | 30.0 | nM | 587.58 | Cc1cccc(C)c1N1C[C@@](CN(CCF)CC2CC2)(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](C)C1=O | Homo sapiens | CHEMBL3880333 | cell-based format |
| CHEMBL3895820 |  |
IC50 | <= | 30.0 | nM | 561.54 | CCN(CCF)C[C@@]1(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CN(c2c(C)cccc2C)C(=O)[C@H]1C | Homo sapiens | CHEMBL3880333 | cell-based format |
| CHEMBL3957569 |  |
IC50 | <= | 30.0 | nM | 547.52 | Cc1cccc(C)c1N1C[C@@](CN(C)CCF)(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](C)C1=O | Homo sapiens | CHEMBL3880333 | cell-based format |
| CHEMBL3954941 |  |
IC50 | <= | 30.0 | nM | 557.58 | CCN(C[C@@]1(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CN(c2c(C)cccc2C)C(=O)[C@H]1C)C(C)C | Homo sapiens | CHEMBL3880333 | cell-based format |
| CHEMBL3945088 |  |
IC50 | <= | 30.0 | nM | 565.51 | Cc1cccc(C)c1N1C[C@@](CN(C)CC(F)F)(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](C)C1=O | Homo sapiens | CHEMBL3880333 | cell-based format |
| CHEMBL3965949 |  |
IC50 | <= | 30.0 | nM | 583.5 | Cc1cccc(C)c1N1C[C@@](CN(C)CC(F)(F)F)(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](C)C1=O | Homo sapiens | CHEMBL3880333 | cell-based format |
| CHEMBL3972821 |  |
IC50 | <= | 30.0 | nM | 500.57 | Cc1cccc(C)c1N1C[C@@](CN(C)C(C)C)(C(=O)Nc2cc(C#N)cc(C(F)(F)F)c2)[C@H](C)C1=O | Homo sapiens | CHEMBL3880333 | cell-based format |
| CHEMBL3892838 |  |
IC50 | <= | 30.0 | nM | 555.56 | Cc1cccc(C)c1N1C[C@@](CN(C)CC2CC2)(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](C)C1=O | Homo sapiens | CHEMBL3880333 | cell-based format |
| CHEMBL3890077 |  |
IC50 | <= | 30.0 | nM | 534.53 | Cc1cccc(C)c1N1C[C@@](CN2CCC(F)(F)C2)(C(=O)Nc2cc(C#N)cc(C(F)(F)F)c2)[C@H](C)C1=O | Homo sapiens | CHEMBL3880333 | cell-based format |
| CHEMBL3904343 |  |
IC50 | <= | 30.0 | nM | 569.59 | CCN(CC1CC1)C[C@@]1(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CN(c2c(C)cccc2C)C(=O)[C@H]1C | Homo sapiens | CHEMBL3880333 | cell-based format |
| CHEMBL3914260 |  |
IC50 | <= | 30.0 | nM | 530.57 | Cc1cccc(C)c1N1C[C@@](CN2CCC(F)CC2)(C(=O)Nc2cc(C#N)cc(C(F)(F)F)c2)[C@H](C)C1=O | Homo sapiens | CHEMBL3880333 | cell-based format |
| CHEMBL3924474 |  |
IC50 | <= | 30.0 | nM | 514.59 | CCN(C[C@@]1(C(=O)Nc2cc(C#N)cc(C(F)(F)F)c2)CN(c2c(C)cccc2C)C(=O)[C@H]1C)C(C)C | Homo sapiens | CHEMBL3880333 | cell-based format |
| CHEMBL3918834 |  |
IC50 | <= | 30.0 | nM | 557.58 | Cc1cccc(C)c1N1C[C@@](CN(C)CC(C)C)(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](C)C1=O | Homo sapiens | CHEMBL3880333 | cell-based format |
| CHEMBL3956379 |  |
IC50 | <= | 30.0 | nM | 543.55 | Cc1cccc(C)c1N1C[C@@](CN(C)C(C)C)(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](C)C1=O | Homo sapiens | CHEMBL3880333 | cell-based format |
| CHEMBL3933822 |  |
IC50 | <= | 30.0 | nM | 589.6 | Cc1cccc(C)c1N1C[C@@](CN(CCF)CC(C)C)(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](C)C1=O | Homo sapiens | CHEMBL3880333 | cell-based format |
| CHEMBL3955594 |  |
IC50 | <= | 30.0 | nM | 486.54 | CCN(C)C[C@@]1(C(=O)Nc2cc(C#N)cc(C(F)(F)F)c2)CN(c2c(C)cccc2C)C(=O)[C@H]1C | Homo sapiens | CHEMBL3880333 | cell-based format |
| CHEMBL3894738 |  |
IC50 | <= | 30.0 | nM | 498.55 | Cc1cccc(C)c1N1C[C@@](CN2CCCC2)(C(=O)Nc2cc(C#N)cc(C(F)(F)F)c2)[C@H](C)C1=O | Homo sapiens | CHEMBL3880333 | cell-based format |
| CHEMBL3956087 |  |
IC50 | <= | 30.0 | nM | 472.51 | Cc1cccc(C)c1N1C[C@@](CN(C)C)(C(=O)Nc2cc(C#N)cc(C(F)(F)F)c2)[C@H](C)C1=O | Homo sapiens | CHEMBL3880333 | cell-based format |
| CHEMBL3903642 |  |
IC50 | <= | 30.0 | nM | 512.58 | Cc1cccc(C)c1N1C[C@@](CN2CCCCC2)(C(=O)Nc2cc(C#N)cc(C(F)(F)F)c2)[C@H](C)C1=O | Homo sapiens | CHEMBL3880333 | cell-based format |