Q99759 | M3K3_HUMAN | Mitogen-activated protein kinase kinase kinase 3 (MAP3K3)

Pfam Domain Table

AccessionDomainRangeColor
PF00069Pkinase - Protein kinase domain364~621
PF00564PB1 - PB1 domain45~120

3D structures mapped by conservation among orthologs

[ Domain: "Ubiquitin-like" // PB1 ]

 PyMOL session


[ Alpha Fold Model ] (go)



Known binders annotated in ChEMBL

 IC50 CSV
Only the first 20 rows are shown.
molecule_chembl_idstructureassay_typerelation valueunitmol_wtsmilesorganism assay_chembl_idbao_label
CHEMBL388978 IC50 = 10.9 nM 466.54 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 Homo sapiens CHEMBL4328493 single protein format
CHEMBL4554938 IC50 = 34.8 nM 416.49 CN1C(=O)c2sccc2N(C)c2nc(Nc3ccc(S(N)(=O)=O)cc3)ncc21 Homo sapiens CHEMBL5212984 single protein format