Q96T60 | PNKP_HUMAN | Bifunctional polynucleotide phosphatase/kinase (PNKP)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF08645 | PNK3P - Polynucleotide kinase 3 phosphatase | 166~328 | |
| PF13671 | AAA_33 - AAA domain | 367~489 | |
| PF17913 | FHA_2 - FHA domain | 11~80 |
3D structures mapped by conservation among orthologs
[ Domain: "SMAD/FHA domain" // FHA_1 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4303462 |  |
IC50 | = | 60.0 | nM | 534.66 | CCCCCCCCCCC(O)C1C=CC2C(=O)N(c3ccccc3)C(=O)C2N1Nc1ccc([N+](=O)[O-])cc1 | Homo sapiens | CHEMBL4419662 | single protein format |
| CHEMBL4450001 |  |
IC50 | = | 300.0 | nM | 560.56 | COc1cc(C(O)C2C=CC3C(=O)N(c4ccccc4)C(=O)C3N2Nc2ccc([N+](=O)[O-])cc2)cc(OC)c1OC | Homo sapiens | CHEMBL4419662 | single protein format |