Q96RJ0 | TAAR1_HUMAN | Trace amine-associated receptor 1 (TAAR1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 - 7 transmembrane receptor (rhodopsin family) | 40~304 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL2206400 |  |
Ki | = | 2.0 | nM | 172.23 | c1ccc(CCc2c[nH]cn2)cc1 | Homo sapiens | CHEMBL2213071 | cell-based format |
| CHEMBL2206385 |  |
Ki | = | 2.0 | nM | 235.72 | CCN(Cc1cnc[nH]1)c1cccc(Cl)c1 | Homo sapiens | CHEMBL2213071 | cell-based format |
| CHEMBL2206376 |  |
Ki | = | 4.0 | nM | 284.19 | CC(C)N(Cc1cnc[nH]1)c1ccc(Cl)c(Cl)c1 | Homo sapiens | CHEMBL2213071 | cell-based format |
| CHEMBL2206377 |  |
Ki | = | 4.0 | nM | 284.19 | CC(C)N(Cc1cnc[nH]1)c1cc(Cl)cc(Cl)c1 | Homo sapiens | CHEMBL2213071 | cell-based format |
| CHEMBL2206890 |  |
Ki | = | 4.0 | nM | 249.75 | CC(C)N(Cc1cnc[nH]1)c1cccc(Cl)c1 | Homo sapiens | CHEMBL2213071 | cell-based format |
| CHEMBL2206381 |  |
Ki | = | 5.0 | nM | 245.33 | COc1cccc(N(Cc2cnc[nH]2)C(C)C)c1 | Homo sapiens | CHEMBL2213071 | cell-based format |
| CHEMBL2206375 |  |
Ki | = | 6.0 | nM | 249.75 | CC(C)N(Cc1cnc[nH]1)c1ccc(Cl)cc1 | Homo sapiens | CHEMBL2213071 | cell-based format |
| CHEMBL2206384 |  |
Ki | = | 11.0 | nM | 221.69 | CN(Cc1cnc[nH]1)c1cccc(Cl)c1 | Homo sapiens | CHEMBL2213071 | cell-based format |
| CHEMBL2206402 |  |
Ki | = | 11.0 | nM | 187.25 | CN(Cc1cnc[nH]1)c1ccccc1 | Homo sapiens | CHEMBL2213071 | cell-based format |
| CHEMBL2206379 |  |
Ki | = | 12.0 | nM | 233.29 | CC(C)N(Cc1c[nH]cn1)c1cccc(F)c1 | Homo sapiens | CHEMBL2213071 | cell-based format |
| CHEMBL2206388 |  |
Ki | = | 12.0 | nM | 246.31 | COc1cccc(N(Cc2cnc[nH]2)C(C)C)n1 | Homo sapiens | CHEMBL2213071 | cell-based format |
| CHEMBL2206408 |  |
Ki | = | 12.0 | nM | 213.28 | c1ccc2c(c1)CCCN2Cc1c[nH]cn1 | Homo sapiens | CHEMBL2213071 | cell-based format |
| CHEMBL2206380 |  |
Ki | = | 13.0 | nM | 233.29 | CC(C)N(Cc1cnc[nH]1)c1ccc(F)cc1 | Homo sapiens | CHEMBL2213071 | cell-based format |
| CHEMBL2206378 |  |
Ki | = | 18.0 | nM | 233.29 | CC(C)N(Cc1c[nH]cn1)c1ccccc1F | Homo sapiens | CHEMBL2213071 | cell-based format |
| CHEMBL494421 |  |
Ki | = | 20.0 | nM | 158.2 | c1ccc(Cc2c[nH]cn2)cc1 | Homo sapiens | CHEMBL2213071 | cell-based format |
| CHEMBL2206404 |  |
Ki | = | 22.0 | nM | 215.3 | CC(C)N(Cc1cnc[nH]1)c1ccccc1 | Homo sapiens | CHEMBL2213071 | cell-based format |
| CHEMBL2206397 |  |
Ki | = | 24.0 | nM | 214.31 | CCc1cccc(CC)c1Cc1ncc[nH]1 | Homo sapiens | CHEMBL2213071 | cell-based format |
| CHEMBL348369 |  |
Ki | = | 32.0 | nM | 263.34 | c1ccc(CN(Cc2c[nH]cn2)c2ccccc2)cc1 | Homo sapiens | CHEMBL2213071 | cell-based format |
| CHEMBL2206386 |  |
Ki | = | 33.0 | nM | 263.77 | CC(C)(C)N(Cc1c[nH]cn1)c1cccc(Cl)c1 | Homo sapiens | CHEMBL2213071 | cell-based format |
| CHEMBL2206407 |  |
Ki | = | 35.0 | nM | 199.26 | c1ccc2c(c1)CCN2Cc1c[nH]cn1 | Homo sapiens | CHEMBL2213071 | cell-based format |