Q96RG2 | PASK_HUMAN | PAS domain-containing serine/threonine-protein kinase (PASK)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 999~1251 | |
| PF13426 | PAS_9 - PAS domain | 133~223 | |
| PF13426 | PAS_9 - PAS domain | 349~385 |
3D structures mapped by conservation among orthologs
[ Domain: "sensor domains" // PAS ]
[ Domain: "Protein kinase" // Pkinase_Tyr ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL388978 |  |
IC50 | = | 15.8 | nM | 466.54 | CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 | Homo sapiens | CHEMBL4328547 | single protein format |
| CHEMBL3775576 |  |
IC50 | = | 260.0 | nM | 319.37 | CNC(=O)c1ccc2[nH]nc(Cc3ccc4c(cnn4C)c3)c2c1 | Homo sapiens | CHEMBL3776910 | single protein format |