Q96Q83 | ALKB3_HUMAN | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (ALKBH3)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF13532 | 2OG-FeII_Oxy_2 - 2OG-Fe(II) oxygenase superfamily | 90~275 |
3D structures mapped by conservation among orthologs
[ Domain: "Double-stranded beta-helix" // 2OG-FeII_Oxy_2 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3145429 |  |
IC50 | = | 480.0 | nM | 304.35 | Cc1[nH]n(-c2nc3ccccc3[nH]2)c(=O)c1Cc1ccccc1 | Homo sapiens | CHEMBL3119218 | single protein format |
| CHEMBL3145446 |  |
IC50 | = | 490.0 | nM | 383.25 | Cc1[nH]n(-c2nc3cc(Br)ccc3[nH]2)c(=O)c1Cc1ccccc1 | Homo sapiens | CHEMBL3119218 | single protein format |
| CHEMBL3145436 |  |
IC50 | = | 540.0 | nM | 338.8 | Cc1[nH]n(-c2nc3ccccc3[nH]2)c(=O)c1Cc1cccc(Cl)c1 | Homo sapiens | CHEMBL3119218 | single protein format |
| CHEMBL3145440 |  |
IC50 | = | 550.0 | nM | 372.35 | Cc1[nH]n(-c2nc3ccccc3[nH]2)c(=O)c1Cc1ccc(C(F)(F)F)cc1 | Homo sapiens | CHEMBL3119218 | single protein format |
| CHEMBL3145451 |  |
IC50 | = | 570.0 | nM | 386.38 | Cc1ccc2[nH]c(-n3[nH]c(C)c(Cc4ccc(C(F)(F)F)cc4)c3=O)nc2c1 | Homo sapiens | CHEMBL3119218 | single protein format |
| CHEMBL3145441 |  |
IC50 | = | 600.0 | nM | 322.34 | Cc1[nH]n(-c2nc3ccccc3[nH]2)c(=O)c1Cc1ccc(F)cc1 | Homo sapiens | CHEMBL3119218 | single protein format |
| CHEMBL3145447 |  |
IC50 | = | 610.0 | nM | 372.35 | Cc1[nH]n(-c2nc3cc(C(F)(F)F)ccc3[nH]2)c(=O)c1Cc1ccccc1 | Homo sapiens | CHEMBL3119218 | single protein format |
| CHEMBL3145442 |  |
IC50 | = | 630.0 | nM | 334.38 | COc1ccc(Cc2c(C)[nH]n(-c3nc4ccccc4[nH]3)c2=O)cc1 | Homo sapiens | CHEMBL3119218 | single protein format |
| CHEMBL3145448 |  |
IC50 | = | 640.0 | nM | 360.46 | Cc1[nH]n(-c2nc3cc(C(C)(C)C)ccc3[nH]2)c(=O)c1Cc1ccccc1 | Homo sapiens | CHEMBL3119218 | single protein format |
| CHEMBL3145419 |  |
IC50 | = | 670.0 | nM | 318.38 | Cc1ccc2[nH]c(-n3[nH]c(C)c(Cc4ccccc4)c3=O)nc2c1 | Homo sapiens | CHEMBL3119218 | single protein format |
| CHEMBL3145452 |  |
IC50 | = | 680.0 | nM | 348.41 | COc1ccc(Cc2c(C)[nH]n(-c3nc4cc(C)ccc4[nH]3)c2=O)cc1 | Homo sapiens | CHEMBL3119218 | single protein format |
| CHEMBL3145410 |  |
IC50 | = | 720.0 | nM | 387.27 | Cc1ccc2[nH]c(-n3[nH]c(C)c(Cc4ccc(Cl)c(Cl)c4)c3=O)nc2c1 | Homo sapiens | CHEMBL3119218 | single protein format |
| CHEMBL3145443 |  |
IC50 | = | 720.0 | nM | 380.45 | Cc1[nH]n(-c2nc3ccccc3[nH]2)c(=O)c1Cc1ccc(-c2ccccc2)cc1 | Homo sapiens | CHEMBL3119218 | single protein format |
| CHEMBL3145412 |  |
IC50 | = | 750.0 | nM | 352.83 | Cc1ccc2[nH]c(-n3[nH]c(C)c(Cc4ccc(Cl)cc4)c3=O)nc2c1 | Homo sapiens | CHEMBL3119218 | single protein format |
| CHEMBL3145430 |  |
IC50 | = | 750.0 | nM | 354.41 | Cc1[nH]n(-c2nc3ccccc3[nH]2)c(=O)c1Cc1ccc2ccccc2c1 | Homo sapiens | CHEMBL3119218 | single protein format |
| CHEMBL3145413 |  |
IC50 | = | 780.0 | nM | 336.37 | Cc1ccc2[nH]c(-n3[nH]c(C)c(Cc4ccc(F)cc4)c3=O)nc2c1 | Homo sapiens | CHEMBL3119218 | single protein format |
| CHEMBL3145449 |  |
IC50 | = | 810.0 | nM | 380.45 | Cc1[nH]n(-c2nc3cc(-c4ccccc4)ccc3[nH]2)c(=O)c1Cc1ccccc1 | Homo sapiens | CHEMBL3119218 | single protein format |
| CHEMBL3145411 |  |
IC50 | = | 910.0 | nM | 352.83 | Cc1ccc2[nH]c(-n3[nH]c(C)c(Cc4ccccc4Cl)c3=O)nc2c1 | Homo sapiens | CHEMBL3119218 | single protein format |