Q96PH1 | NOX5_HUMAN | NADPH oxidase 5 (NOX5)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01794 | Ferric_reduct | 286–412 | |
| PF08022 | FAD_binding_8 | 446–574 | |
| PF08030 | NAD_binding_6 | 583–753 | |
| PF13202 | EF-hand_5 | 172–192 | |
| PF13405 | EF-hand_6 | 63–88 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL397686 |  |
IC50 | = | 20.0 | nM | 314.55 | [Cl-].c1ccc2c(c1)[I+]c1ccccc1-2 | Homo sapiens | CHEMBL5367009 | cell-based format |
| CHEMBL5218591 |  |
IC50 | = | 570.0 | nM | 389.51 | Cc1ccc(N2CCN(c3nc(N)nc(Nc4ccc(C)c(C)c4)n3)CC2)cc1 | Homo sapiens | CHEMBL5216595 | single protein format |
| CHEMBL5398181 |  |
IC50 | = | 570.0 | nM | 403.53 | Cc1ccc(N2CCN(Cc3nc(N)nc(Nc4ccc(C)c(C)c4)n3)CC2)cc1 | Homo sapiens | CHEMBL5367044 | single protein format |
| CHEMBL4303187 |  |
Ki | = | 410.0 | nM | 394.86 | CN(C)c1cccc(-c2c3c(=O)n(-c4ccccc4Cl)[nH]c3cc(=O)n2C)c1 | Homo sapiens | CHEMBL5367027 | single protein format |