Q96PC2 | IP6K3_HUMAN | Inositol hexakisphosphate kinase 3 (IP6K3)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF03770 | IPK | 198–404 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5203174 |  |
IC50 | = | 8.0 | nM | 384.82 | O=C(O)c1ccc2c(c1)C1(CCN(C(=O)c3ccc(Cl)cc3)CC1)C(=O)N2 | Homo sapiens | CHEMBL5166050 | single protein format |
| CHEMBL5181623 |  |
IC50 | = | 200.0 | nM | 341.37 | O=C(O)/C=C/c1ccc2noc(-c3ccc(-c4ccccc4)cc3)c2c1 | Homo sapiens | CHEMBL5166046 | assay format |
| CHEMBL5171388 |  |
IC50 | = | 200.0 | nM | 358.35 | O=C(O)c1ccc2noc(-c3ccc(NC(=O)c4ccccc4)cc3)c2c1 | Homo sapiens | CHEMBL5166046 | assay format |
| CHEMBL5206215 |  |
IC50 | = | 210.0 | nM | 324.34 | CC(C)C(=O)Nc1ccc(-c2onc3ccc(C(=O)O)cc23)cc1 | Homo sapiens | CHEMBL5166046 | assay format |
| CHEMBL5190343 |  |
IC50 | = | 240.0 | nM | 315.33 | O=C(O)c1ccc2noc(-c3ccc(-c4ccccc4)cc3)c2c1 | Homo sapiens | CHEMBL5166046 | assay format |
| CHEMBL5197626 |  |
IC50 | = | 240.0 | nM | 350.37 | O=C(O)c1ccc2noc(-c3ccc(NC(=O)C4CCCC4)cc3)c2c1 | Homo sapiens | CHEMBL5166046 | assay format |
| CHEMBL5198845 |  |
IC50 | = | 340.0 | nM | 324.34 | CC(C)NC(=O)c1ccc(-c2onc3ccc(C(=O)O)cc23)cc1 | Homo sapiens | CHEMBL5166046 | assay format |
| CHEMBL5185229 |  |
IC50 | = | 430.0 | nM | 360.33 | O=C(O)c1ccc2noc(-c3ccc(NC(=O)c4ccncn4)cc3)c2c1 | Homo sapiens | CHEMBL5166046 | assay format |
| CHEMBL5185725 |  |
IC50 | = | 550.0 | nM | 331.33 | O=C(O)c1ccc2noc(-c3ccc(Oc4ccccc4)cc3)c2c1 | Homo sapiens | CHEMBL5166046 | assay format |
| CHEMBL5169462 |  |
IC50 | = | 610.0 | nM | 316.32 | O=C(O)c1ccc2noc(-c3ccc(-c4cccnc4)cc3)c2c1 | Homo sapiens | CHEMBL5166046 | assay format |
| CHEMBL5201078 |  |
IC50 | = | 670.0 | nM | 316.32 | O=C(O)c1ccc2noc(-c3ccc(-c4ccncc4)cc3)c2c1 | Homo sapiens | CHEMBL5166046 | assay format |
| CHEMBL5184960 |  |
IC50 | = | 760.0 | nM | 357.37 | O=C(O)/C=C/c1ccc2noc(-c3ccc(Oc4ccccc4)cc3)c2c1 | Homo sapiens | CHEMBL5166046 | assay format |
| CHEMBL5184940 |  |
IC50 | = | 840.0 | nM | 315.33 | O=C(O)c1ccc2noc(-c3cccc(-c4ccccc4)c3)c2c1 | Homo sapiens | CHEMBL5166046 | assay format |
| CHEMBL5196483 |  |
IC50 | = | 850.0 | nM | 331.33 | O=C(O)c1ccc2noc(-c3cccc(Oc4ccccc4)c3)c2c1 | Homo sapiens | CHEMBL5166046 | assay format |