Q96P65 | QRFPR_HUMAN | Pyroglutamylated RF-amide peptide receptor (QRFPR)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 - 7 transmembrane receptor (rhodopsin family) | 62~332 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3314362 |  |
IC50 | = | 40.0 | nM | 395.93 | Cc1cc2c(cc1CN(C)C)CCN(C(=O)c1cc3cc(Cl)ccc3n1C)C2 | Homo sapiens | CHEMBL3368109 | cell-based format |
| CHEMBL3314349 |  |
IC50 | = | 70.0 | nM | 381.91 | CN(C)Cc1ccc2c(c1)CCN(C(=O)c1cc3cc(Cl)ccc3n1C)C2 | Homo sapiens | CHEMBL3368109 | cell-based format |
| CHEMBL3314358 |  |
IC50 | = | 110.0 | nM | 441.37 | CC1CN(C(=O)c2cc3cc(Br)ncc3n2C)Cc2ccc(CN(C)C)cc21 | Homo sapiens | CHEMBL3368108 | cell-based format |
| CHEMBL3314354 |  |
IC50 | = | 130.0 | nM | 474.35 | CN(C)Cc1ccc2c(c1)CCN(C(=O)c1cc3cc(I)ncc3n1C)C2 | Homo sapiens | CHEMBL3368108 | cell-based format |
| CHEMBL3314352 |  |
IC50 | = | 280.0 | nM | 427.35 | CN(C)Cc1ccc2c(c1)CCN(C(=O)c1cc3cc(Br)ncc3n1C)C2 | Homo sapiens | CHEMBL3368109 | cell-based format |
| CHEMBL3314361 |  |
IC50 | = | 460.0 | nM | 396.92 | CC(c1ccc2c(c1)CCN(C(=O)c1cc3cc(Cl)ncc3n1C)C2)N(C)C | Homo sapiens | CHEMBL3368108 | cell-based format |
| CHEMBL3314359 |  |
IC50 | = | 500.0 | nM | 396.92 | CC1c2ccc(CN(C)C)cc2CCN1C(=O)c1cc2cc(Cl)ncc2n1C | Homo sapiens | CHEMBL3368108 | cell-based format |
| CHEMBL3314350 |  |
IC50 | = | 570.0 | nM | 382.9 | CN(C)Cc1ccc2c(c1)CCN(C(=O)c1cc3cc(Cl)ncc3n1C)C2 | Homo sapiens | CHEMBL3368108 | cell-based format |
| CHEMBL3314360 |  |
IC50 | = | 710.0 | nM | 396.92 | CC1Cc2cc(CN(C)C)ccc2CN1C(=O)c1cc2cc(Cl)ncc2n1C | Homo sapiens | CHEMBL3368108 | cell-based format |