Q96LB2 | MRGX1_HUMAN | Mas-related G-protein coupled receptor member X1 (MRGPRX1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 - 7 transmembrane receptor (rhodopsin family) | 44~272 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3730717 |  |
IC50 | = | 182.0 | nM | 425.57 | COc1ccccc1C(O)/C=C1\C2CCN(CC2)C1C(c1ccccc1)c1ccccc1 | Homo sapiens | CHEMBL3734551 | single protein format |
| CHEMBL3730599 |  |
IC50 | = | 607.0 | nM | 446.98 | O=C(Nc1ccccc1Cl)O[C@@H]1C2CCN(CC2)C1C(c1ccccc1)c1ccccc1 | Homo sapiens | CHEMBL3734551 | single protein format |
| CHEMBL3727861 |  |
IC50 | = | 630.0 | nM | 413.54 | OC(/C=C1\C2CCN(CC2)C1C(c1ccccc1)c1ccccc1)c1ccc(F)cc1 | Homo sapiens | CHEMBL3734551 | single protein format |
| CHEMBL3343995 |  |
IC50 | = | 800.0 | nM | 423.56 | COc1ccccc1C(=O)/C=C1\C2CCN(CC2)C1C(c1ccccc1)c1ccccc1 | Homo sapiens | CHEMBL3388388 | cell-based format |