Q93088 | BHMT1_HUMAN | Betaine--homocysteine S-methyltransferase 1 (BHMT)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF02574 | S-methyl_trans - Homocysteine S-methyltransferase | 23~314 |
3D structures mapped by conservation among orthologs
[ Domain: "TIM barrels" // S-methyl_trans ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL488121 |  |
IC50 | = | 64.0 | nM | 263.36 | CC(C)(CCSCC[C@H](N)C(=O)O)CC(=O)O | Homo sapiens | CHEMBL947843 | assay format |
| CHEMBL443372 |  |
IC50 | = | 84.0 | nM | 263.36 | CC(C)(CCSCCC(N)C(=O)O)CC(=O)O | Homo sapiens | CHEMBL947843 | assay format |
| CHEMBL211229 |  |
IC50 | = | 87.0 | nM | 235.3 | NC(CCSCCCCC(=O)O)C(=O)O | Homo sapiens | CHEMBL865953 | single protein format |
| CHEMBL211961 |  |
IC50 | = | 96.0 | nM | 253.34 | NC(CCSCCSCC(=O)O)C(=O)O | Homo sapiens | CHEMBL865953 | single protein format |
| CHEMBL486279 |  |
IC50 | = | 139.0 | nM | 249.33 | CC(CCSCCC(N)C(=O)O)CC(=O)O | Homo sapiens | CHEMBL947843 | assay format |
| CHEMBL208607 |  |
IC50 | = | 200.0 | nM | 249.33 | NC(CCSCCCCCC(=O)O)C(=O)O | Homo sapiens | CHEMBL865953 | single protein format |
| CHEMBL448548 |  |
IC50 | = | 649.0 | nM | 282.2 | NC(CC[Se]CCCCC(=O)O)C(=O)O | Homo sapiens | CHEMBL947843 | assay format |
| CHEMBL442625 |  |
IC50 | = | 701.0 | nM | 263.36 | CC(C)(CCSCC[C@@H](N)C(=O)O)CC(=O)O | Homo sapiens | CHEMBL947843 | assay format |