Q92952 | KCNN1_HUMAN | Small conductance calcium-activated potassium channel protein 1 (KCNN1)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF02888 | CaMBD | 384–461 | |
| PF03530 | SK_channel | 92–207 | |
| PF07885 | Ion_trans_2 | 291–369 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL476339 |  |
IC50 | = | 4.0 | nM | 268.35 | Cc1ccnc(Nc2nc(-c3ccccn3)cs2)c1 | Homo sapiens | CHEMBL986174 | cell-based format |
| CHEMBL489770 |  |
IC50 | = | 43.0 | nM | 254.32 | c1ccc(Nc2nc(-c3ccccn3)cs2)nc1 | Homo sapiens | CHEMBL986174 | cell-based format |
| CHEMBL472452 |  |
IC50 | = | 300.0 | nM | 264.74 | Clc1cc(NCc2cccs2)n2nccc2n1 | Homo sapiens | CHEMBL995895 | cell-based format |