Q92934 | BAD_HUMAN | Bcl2-associated agonist of cell death (BAD)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF10514 | Bcl-2_BAD - Pro-apoptotic Bcl-2 protein, BAD | 1~168 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL402005 |  |
IC50 | = | 36.0 | nM | 539.61 | O=C(NS(=O)(=O)c1ccc(NCCS2=CC=CC=C2)c([N+](=O)[O-])c1)c1ccc(-c2ccc(F)cc2)cc1 | Homo sapiens | CHEMBL925858 | single protein format |
| CHEMBL481581 |  |
IC50 | = | 250.0 | nM | 536.12 | CCCCN(CCCC)C(=O)c1nn(-c2ccccc2C(=O)N2Cc3ccccc3C[C@H]2CN)c(C)c1Cl | Homo sapiens | CHEMBL1019893 | single protein format |
| CHEMBL4872320 |  |
Ki | = | 100.0 | nM | 487.99 | O=C(O)c1ccccc1-c1cccc2c1c(-c1cccc(Cl)c1)cn2Cc1cccc2ccccc12 | Homo sapiens | CHEMBL4813625 | single protein format |
| CHEMBL4872671 |  |
Ki | = | 250.0 | nM | 551.56 | O=C(O)c1ccccc1-c1cccc2c1c(-c1cccc(C(F)(F)F)c1)cn2CCOc1cccc2ccccc12 | Homo sapiens | CHEMBL4813625 | single protein format |
| CHEMBL4864929 |  |
Ki | = | 250.0 | nM | 497.59 | Cc1ccccc1-c1cn(CCOc2cccc3ccccc23)c2cccc(-c3ccccc3C(=O)O)c12 | Homo sapiens | CHEMBL4813625 | single protein format |
| CHEMBL4855114 |  |
Ki | = | 300.0 | nM | 511.62 | CCc1ccccc1-c1cn(CCOc2cccc3ccccc23)c2cccc(-c3ccccc3C(=O)O)c12 | Homo sapiens | CHEMBL4813625 | single protein format |
| CHEMBL4870608 |  |
Ki | = | 360.0 | nM | 497.59 | Cc1cccc(-c2cn(CCOc3cccc4ccccc34)c3cccc(-c4ccccc4C(=O)O)c23)c1 | Homo sapiens | CHEMBL4813625 | single protein format |
| CHEMBL51483 |  |
Ki | = | 460.0 | nM | 518.56 | Cc1cc2c(C(C)C)c(O)c(O)c(C=O)c2c(O)c1-c1c(C)cc2c(C(C)C)c(O)c(O)c(C=O)c2c1O | Homo sapiens | CHEMBL4813625 | single protein format |
| CHEMBL4860820 |  |
Ki | = | 490.0 | nM | 455.94 | O=C(O)c1ccc(Cl)cc1-c1cccc2c1ccn2CCCOc1cccc2ccccc12 | Homo sapiens | CHEMBL4813625 | single protein format |
| CHEMBL4852823 |  |
Ki | = | 530.0 | nM | 483.57 | COc1cccc(-c2cn(Cc3cccc4ccccc34)c3cccc(-c4ccccc4C(=O)O)c23)c1 | Homo sapiens | CHEMBL4813625 | single protein format |
| CHEMBL4864735 |  |
Ki | = | 560.0 | nM | 511.62 | Cc1cccc(-c2cn(CCCOc3cccc4ccccc34)c3cccc(-c4ccccc4C(=O)O)c23)c1 | Homo sapiens | CHEMBL4813625 | single protein format |
| CHEMBL4870458 |  |
Ki | = | 660.0 | nM | 467.57 | Cc1ccccc1-c1cn(Cc2cccc3ccccc23)c2cccc(-c3ccccc3C(=O)O)c12 | Homo sapiens | CHEMBL4813625 | single protein format |
| CHEMBL4846508 |  |
Ki | = | 800.0 | nM | 467.57 | Cc1ccc(-c2cn(Cc3cccc4ccccc34)c3cccc(-c4ccccc4C(=O)O)c23)cc1 | Homo sapiens | CHEMBL4813625 | single protein format |
| CHEMBL4856143 |  |
Ki | = | 820.0 | nM | 513.59 | COc1ccccc1-c1cn(CCOc2cccc3ccccc23)c2cccc(-c3ccccc3C(=O)O)c12 | Homo sapiens | CHEMBL4813625 | single protein format |
| CHEMBL4870837 |  |
Ki | = | 820.0 | nM | 453.54 | O=C(O)c1ccccc1-c1cccc2c1c(-c1ccccc1)cn2Cc1cccc2ccccc12 | Homo sapiens | CHEMBL4813625 | single protein format |
| CHEMBL4876348 |  |
Ki | = | 870.0 | nM | 497.59 | Cc1ccc(-c2cn(CCOc3cccc4ccccc34)c3cccc(-c4ccccc4C(=O)O)c23)cc1 | Homo sapiens | CHEMBL4813625 | single protein format |
| CHEMBL408194 |  |
Ki | = | 1000.0 | nM | 317.39 | COC1=CC(c2cc3ccccc3[nH]2)=N/C1=C\c1[nH]c(C)cc1C | Homo sapiens | CHEMBL936491 | single protein format |