Q92830 | KAT2A_HUMAN | Histone acetyltransferase KAT2A (KAT2A)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00439 | Bromodomain - Bromodomain | 738~818 | |
| PF00583 | Acetyltransf_1 - Acetyltransferase (GNAT) family | 535~627 | |
| PF06466 | PCAF_N - PCAF (P300/CBP-associated factor) N-terminal domain | 86~336 |
3D structures mapped by conservation among orthologs
[ Domain: "Bromodomain" // Bromodomain ]
[ Domain: "Acyl-CoA N-acyltransferases (Nat)" // Acetyltransf_10 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4570969 |  |
IC50 | = | 220.0 | nM | 360.47 | Cc1nnc2c3ccccc3c(N[C@@H](C)[C@H](c3ccccc3)N(C)C)nn12 | Homo sapiens | CHEMBL5210228 | single protein format |
| CHEMBL4069412 |  |
Ki | = | 1.4 | nM | 377.29 | CN1C[C@H](Nc2cnn(C)c(=O)c2Br)C[C@H](c2ccccc2)C1 | Homo sapiens | CHEMBL4003548 | assay format |