Q92551 | IP6K1_HUMAN | Inositol hexakisphosphate kinase 1 (IP6K1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF03770 | IPK - Inositol polyphosphate kinase | 207~434 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5190343 |  |
IC50 | = | 8.9 | nM | 315.33 | O=C(O)c1ccc2noc(-c3ccc(-c4ccccc4)cc3)c2c1 | Homo sapiens | CHEMBL5166043 | assay format |
| CHEMBL5169462 |  |
IC50 | = | 26.0 | nM | 316.32 | O=C(O)c1ccc2noc(-c3ccc(-c4cccnc4)cc3)c2c1 | Homo sapiens | CHEMBL5166044 | assay format |
| CHEMBL5181623 |  |
IC50 | = | 27.0 | nM | 341.37 | O=C(O)/C=C/c1ccc2noc(-c3ccc(-c4ccccc4)cc3)c2c1 | Homo sapiens | CHEMBL5166044 | assay format |
| CHEMBL5203174 |  |
IC50 | = | 27.0 | nM | 384.82 | O=C(O)c1ccc2c(c1)C1(CCN(C(=O)c3ccc(Cl)cc3)CC1)C(=O)N2 | Homo sapiens | CHEMBL5166049 | single protein format |
| CHEMBL5200214 |  |
IC50 | = | 78.0 | nM | 401.21 | O=C(O)c1ccc2noc(-c3cccc(Oc4ncc(Cl)cc4Cl)c3)c2c1 | Homo sapiens | CHEMBL5166044 | assay format |
| CHEMBL5184940 |  |
IC50 | = | 81.0 | nM | 315.33 | O=C(O)c1ccc2noc(-c3cccc(-c4ccccc4)c3)c2c1 | Homo sapiens | CHEMBL5166044 | assay format |
| CHEMBL5204881 |  |
IC50 | = | 84.0 | nM | 267.28 | Cc1cc(C)cc(-c2onc3ccc(C(=O)O)cc23)c1 | Homo sapiens | CHEMBL5166044 | assay format |
| CHEMBL5186210 |  |
IC50 | = | 110.0 | nM | 329.36 | O=C(O)c1ccc2noc(-c3ccc(Cc4ccccc4)cc3)c2c1 | Homo sapiens | CHEMBL5166044 | assay format |
| CHEMBL5184960 |  |
IC50 | = | 130.0 | nM | 357.37 | O=C(O)/C=C/c1ccc2noc(-c3ccc(Oc4ccccc4)cc3)c2c1 | Homo sapiens | CHEMBL5166044 | assay format |
| CHEMBL5201056 |  |
IC50 | = | 130.0 | nM | 349.26 | O=C(O)/C=C/c1ccc2noc(-c3ccc(OC(F)(F)F)cc3)c2c1 | Homo sapiens | CHEMBL5166044 | assay format |
| CHEMBL5190846 |  |
IC50 | = | 160.0 | nM | 279.3 | Cc1cccc(-c2onc3ccc(/C=C/C(=O)O)cc23)c1 | Homo sapiens | CHEMBL5166044 | assay format |
| CHEMBL5196483 |  |
IC50 | = | 170.0 | nM | 331.33 | O=C(O)c1ccc2noc(-c3cccc(Oc4ccccc4)c3)c2c1 | Homo sapiens | CHEMBL5166044 | assay format |
| CHEMBL5201078 |  |
IC50 | = | 170.0 | nM | 316.32 | O=C(O)c1ccc2noc(-c3ccc(-c4ccncc4)cc3)c2c1 | Homo sapiens | CHEMBL5166044 | assay format |
| CHEMBL5197626 |  |
IC50 | = | 190.0 | nM | 350.37 | O=C(O)c1ccc2noc(-c3ccc(NC(=O)C4CCCC4)cc3)c2c1 | Homo sapiens | CHEMBL5166044 | assay format |
| CHEMBL5175579 |  |
IC50 | = | 240.0 | nM | 322.36 | O=C(O)c1ccc2noc(-c3ccc(N4CCCCC4)cc3)c2c1 | Homo sapiens | CHEMBL5166044 | assay format |
| CHEMBL5186729 |  |
IC50 | = | 280.0 | nM | 253.26 | Cc1cccc(-c2onc3ccc(C(=O)O)cc23)c1 | Homo sapiens | CHEMBL5166044 | assay format |
| CHEMBL5188320 |  |
IC50 | = | 320.0 | nM | 322.32 | O=C(O)c1ccc2noc(-c3ccc(N4CCCC4=O)cc3)c2c1 | Homo sapiens | CHEMBL5166044 | assay format |
| CHEMBL5198845 |  |
IC50 | = | 370.0 | nM | 324.34 | CC(C)NC(=O)c1ccc(-c2onc3ccc(C(=O)O)cc23)cc1 | Homo sapiens | CHEMBL5166044 | assay format |
| CHEMBL5192487 |  |
IC50 | = | 430.0 | nM | 401.21 | O=C(O)c1ccc2noc(-c3ccc(Oc4ncc(Cl)cc4Cl)cc3)c2c1 | Homo sapiens | CHEMBL5166044 | assay format |
| CHEMBL5206215 |  |
IC50 | = | 430.0 | nM | 324.34 | CC(C)C(=O)Nc1ccc(-c2onc3ccc(C(=O)O)cc23)cc1 | Homo sapiens | CHEMBL5166044 | assay format |