Q92523 | CPT1B_HUMAN | Carnitine O-palmitoyltransferase 1, muscle isoform (CPT1B)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00755 | Carn_acyltransf - Choline/Carnitine o-acyltransferase | 176~755 | |
| PF16484 | CPT_N - Carnitine O-palmitoyltransferase N-terminus | 1~47 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3431544 |  |
IC50 | = | 133.95 | nM | 542.96 | COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ccc(C(=O)Nc3ccc(-c4noc(=O)[nH]4)cc3)cc21 | Homo sapiens | CHEMBL3431930 | single protein format |
| CHEMBL3431722 |  |
IC50 | = | 145.3 | nM | 487.96 | COc1ccc(Cl)cc1S(=O)(=O)N1CCCc2ccc(Oc3ccc(CC(=O)O)cc3)cc21 | Homo sapiens | CHEMBL3431930 | single protein format |
| CHEMBL2216771 |  |
IC50 | = | 160.0 | nM | 342.37 | O=C(O)C(=O)c1ccc(OCCOc2ccc3ccccc3c2)s1 | Homo sapiens | CHEMBL2217071 | single protein format |
| CHEMBL3431461 |  |
IC50 | = | 202.0 | nM | 505.96 | COc1ccc(Cl)cc1S(=O)(=O)c1c[nH]c2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc12 | Homo sapiens | CHEMBL3431930 | single protein format |
| CHEMBL3431514 |  |
IC50 | = | 226.05 | nM | 454.9 | O=C(Nc1ccc(-c2nnn[nH]2)cc1)c1cccc(NS(=O)(=O)c2cccc(Cl)c2)c1 | Homo sapiens | CHEMBL3431930 | single protein format |
| CHEMBL3431634 |  |
IC50 | = | 235.3 | nM | 498.94 | COc1ccc(Cl)cc1S(=O)(=O)c1c[nH]c2ccc(C(=O)Nc3ccc(CC(=O)O)cc3)cc12 | Homo sapiens | CHEMBL3431930 | single protein format |
| CHEMBL3431771 |  |
IC50 | = | 259.2 | nM | 549.03 | COc1ccc(Cl)cc1S(=O)(=O)N1CC[S+]([O-])c2ccc(C(=O)Nc3ccc(CC(=O)O)cc3)cc21 | Homo sapiens | CHEMBL3431930 | single protein format |
| CHEMBL3431764 |  |
IC50 | = | 399.5 | nM | 536.99 | COc1ccc(Cl)cc1S(=O)(=O)N1CCSc2ccc(C(=O)Nc3ccc(C(=O)O)c(F)c3)cc21 | Homo sapiens | CHEMBL3431930 | single protein format |
| CHEMBL3431638 |  |
IC50 | = | 423.3 | nM | 523.98 | COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 | Homo sapiens | CHEMBL3431930 | single protein format |
| CHEMBL3431685 |  |
IC50 | = | 438.6 | nM | 489.96 | Cn1cc(S(=O)(=O)c2cccc(Cl)c2)c2cc(C(=O)Nc3nc(CC(=O)O)cs3)ccc21 | Homo sapiens | CHEMBL3431930 | single protein format |
| CHEMBL3431819 |  |
IC50 | = | 447.0 | nM | 514.99 | COc1ccc(Cl)cc1S(=O)(=O)N1CCc2c(C)cc(C(=O)Nc3ccc(CC(=O)O)cc3)cc21 | Homo sapiens | CHEMBL3431930 | single protein format |
| CHEMBL3431728 |  |
IC50 | = | 490.7 | nM | 448.91 | COc1ccc(Cl)cc1Cc1c[nH]c2ccc(C(=O)Nc3ccc(CC(=O)O)cc3)cc12 | Homo sapiens | CHEMBL3431930 | single protein format |
| CHEMBL3431471 |  |
IC50 | = | 504.35 | nM | 502.93 | COc1ccc(Cl)cc1S(=O)(=O)N1COc2ccc(C(=O)Nc3ccc(CC(=O)O)cc3)cc21 | Homo sapiens | CHEMBL3431930 | single protein format |
| CHEMBL3431766 |  |
IC50 | = | 511.9 | nM | 370.41 | O=C(Cn1cc(-c2ccccc2)c2ccccc21)Nc1ccc(C(=O)O)cc1 | Homo sapiens | CHEMBL3431930 | single protein format |
| CHEMBL3431919 |  |
IC50 | = | 527.9 | nM | 484.92 | COc1ccc(Cl)cc1S(=O)(=O)c1c[nH]c2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc12 | Homo sapiens | CHEMBL3431930 | single protein format |
| CHEMBL3431752 |  |
IC50 | = | 530.7 | nM | 471.56 | Cc1cc(C)cc(S(=O)(=O)N2CCc3ccc(C(=O)Nc4nc(CC(=O)O)cs4)cc32)c1 | Homo sapiens | CHEMBL3431930 | single protein format |
| CHEMBL3431632 |  |
IC50 | = | 535.2 | nM | 499.98 | COc1ccc(Cl)cc1CN1C(=O)C(C)(C)c2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 | Homo sapiens | CHEMBL3431930 | single protein format |
| CHEMBL3431622 |  |
IC50 | = | 552.9 | nM | 527.94 | COc1ccc(Cl)cc1S(=O)(=O)N1COc2c(F)cc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 | Homo sapiens | CHEMBL3431930 | single protein format |
| CHEMBL3431893 |  |
IC50 | = | 597.9 | nM | 561.01 | COc1ccc(Cl)cc1S(=O)(=O)N(c1cc(C(=O)Nc2ccc(CC(=O)O)cc2)cc2c1OCO2)C(C)C | Homo sapiens | CHEMBL3431930 | single protein format |
| CHEMBL3431753 |  |
IC50 | = | 601.1 | nM | 477.95 | O=C(O)Cc1csc(NC(=O)c2ccc3c(c2)N(S(=O)(=O)c2cccc(Cl)c2)CC3)n1 | Homo sapiens | CHEMBL3431930 | single protein format |