Q8WTV0 | SCRB1_HUMAN | Scavenger receptor class B member 1 (SCARB1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01130 | CD36 - CD36 family | 16~462 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL2179510 |  |
IC50 | = | 1.5 | nM | 439.53 | Cc1noc(-c2ccc3c(c2)c2c(n3CCCSc3cc(F)cc(F)c3)CCCC2)n1 | Homo sapiens | CHEMBL2184230 | cell-based format |
| CHEMBL2179485 |  |
IC50 | = | 1.5 | nM | 459.55 | CCc1cc(CC)nc(OCCCn2c3c(c4cc(-c5nc(C)no5)ccc42)C(=O)CCC3)n1 | Homo sapiens | CHEMBL2184660 | cell-based format |
| CHEMBL2179507 |  |
IC50 | = | 1.5 | nM | 431.54 | CCc1cc(CC)nc(OCCCn2c3c(c4cc(-n5cnnn5)ccc42)CCCC3)n1 | Homo sapiens | CHEMBL2184660 | cell-based format |
| CHEMBL2179508 |  |
IC50 | = | 1.5 | nM | 423.46 | Cc1noc(-c2ccc3c(c2)c2c(n3CCCOc3cc(F)cc(F)c3)CCCC2)n1 | Homo sapiens | CHEMBL2184660 | cell-based format |
| CHEMBL2179511 |  |
IC50 | = | 1.5 | nM | 439.53 | Cc1noc(-c2ccc3c(c2)c2c(n3CCCSc3ccc(F)c(F)c3)CCCC2)n1 | Homo sapiens | CHEMBL2184660 | cell-based format |
| CHEMBL2179509 |  |
IC50 | = | 1.5 | nM | 423.46 | Cc1noc(-c2ccc3c(c2)c2c(n3CCCOc3ccc(F)c(F)c3)CCCC2)n1 | Homo sapiens | CHEMBL2184660 | cell-based format |
| CHEMBL2179514 |  |
IC50 | = | 1.5 | nM | 429.5 | Cc1noc(-c2ccc3c(c2)c2c(n3CCCc3nc4cc(F)ccc4[nH]3)CCCC2)n1 | Homo sapiens | CHEMBL2184660 | cell-based format |
| CHEMBL2179515 |  |
IC50 | = | 1.5 | nM | 441.45 | Cc1noc(-c2ccc3c(c2)c2c(n3CC(F)COc3cc(F)cc(F)c3)CCCC2)n1 | Homo sapiens | CHEMBL2184660 | cell-based format |
| CHEMBL2179502 |  |
IC50 | = | 1.5 | nM | 402.52 | Cc1noc(-c2ccc3c(c2)c2c(n3CCCS(=O)(=O)N(C)C)CCCC2)n1 | Homo sapiens | CHEMBL2184660 | cell-based format |
| CHEMBL2179501 |  |
IC50 | = | 1.5 | nM | 471.48 | Cc1cc(C(F)(F)F)nc(OCCCn2c3c(c4cc(-c5nc(C)no5)ccc42)CCCC3)n1 | Homo sapiens | CHEMBL2184660 | cell-based format |
| CHEMBL2179493 |  |
IC50 | = | 1.5 | nM | 408.5 | CCc1cc(CC)nc(OCCCn2c3c(c4cc([N+](=O)[O-])ccc42)CCCC3)n1 | Homo sapiens | CHEMBL2184660 | cell-based format |
| CHEMBL2179499 |  |
IC50 | = | 1.5 | nM | 417.51 | Cc1cc(C)nc(OCCCn2c3c(c4cc(-c5nc(C)no5)ccc42)CCCC3)n1 | Homo sapiens | CHEMBL2184660 | cell-based format |
| CHEMBL2179500 |  |
IC50 | = | 1.5 | nM | 445.57 | CCc1cc(CC)nc(OCCCn2c3c(c4cc(-c5nc(C)no5)ccc42)CCCC3)n1 | Homo sapiens | CHEMBL2184660 | cell-based format |
| CHEMBL2179504 |  |
IC50 | = | 1.5 | nM | 402.5 | Cc1cc(C)nc(OCCCn2c3c(c4cc(-c5ncco5)ccc42)CCCC3)n1 | Homo sapiens | CHEMBL2184660 | cell-based format |
| CHEMBL1914885 |  |
IC50 | = | 1.5 | nM | 393.49 | COC(=O)c1ccc2c(c1)c1c(n2CCCOc2nc(C)cc(C)n2)CCCC1 | Homo sapiens | CHEMBL2184660 | cell-based format |
| CHEMBL2179512 |  |
IC50 | = | 5.0 | nM | 471.53 | Cc1noc(-c2ccc3c(c2)c2c(n3CCCS(=O)(=O)c3cc(F)cc(F)c3)CCCC2)n1 | Homo sapiens | CHEMBL2184660 | cell-based format |
| CHEMBL2179497 |  |
IC50 | = | 5.0 | nM | 445.57 | CCc1cc(CC)nc(OCCCn2c3c(c4cc(-c5noc(C)n5)ccc42)CCCC3)n1 | Homo sapiens | CHEMBL2184660 | cell-based format |
| CHEMBL2179106 |  |
IC50 | = | 5.0 | nM | 453.51 | Cc1noc(-c2ccc3c(c2)c2c(n3CCCSc3cc(F)cc(F)c3)CCCC2=O)n1 | Homo sapiens | CHEMBL2184660 | cell-based format |
| CHEMBL2179488 |  |
IC50 | = | 10.0 | nM | 444.56 | COc1cc(OC)nc(NCCCn2c3c(c4cc(S(C)(=O)=O)ccc42)CCCC3)n1 | Homo sapiens | CHEMBL2184660 | cell-based format |
| CHEMBL2179498 |  |
IC50 | = | 15.0 | nM | 445.57 | CCc1cc(CC)nc(OCCCn2c3c(c4cc(-c5nnc(C)o5)ccc42)CCCC3)n1 | Homo sapiens | CHEMBL2184660 | cell-based format |