Q8WTS6 | SETD7_HUMAN | Histone-lysine N-methyltransferase SETD7 (SETD7)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00856 | SET - SET domain | 227~336 | |
| PF02493 | MORN - MORN repeat | 19~34 | |
| PF02493 | MORN - MORN repeat | 36~58 | |
| PF02493 | MORN - MORN repeat | 60~81 | |
| PF22648 | SET7_N - Histone H3 K4-specific methyltransferase SET7 N-terminal | 110~183 |
3D structures mapped by conservation among orthologs
[ Domain: "SET domain-like" // SET ]
[ Domain: "Histone H3 K4-specific methyltransferase SET7/9-N" // KOG1079_3rd_1 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3414622 |  |
IC50 | = | 2.0 | nM | 499.53 | O=C([C@@H](Cc1cccc(C(F)(F)F)c1)NS(=O)(=O)c1cc(F)c2c(c1)CCNC2)N1CCCC1 | Homo sapiens | CHEMBL3420688 | assay format |
| CHEMBL4789678 |  |
IC50 | = | 2.0 | nM | 535.99 | Cl.O=C([C@@H](Cc1cccc(C(F)(F)F)c1)NS(=O)(=O)c1cc(F)c2c(c1)CCNC2)N1CCCC1 | Homo sapiens | CHEMBL5210605 | single protein format |
| CHEMBL516 |  |
IC50 | = | 1000.0 | nM | 287.41 | CN1CCC(=C2c3ccccc3C=Cc3ccccc32)CC1 | Homo sapiens | CHEMBL3812774 | assay format |