Q8TE04 | PANK1_HUMAN | Pantothenate kinase 1 (PANK1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF03630 | Fumble - Fumble | 238~589 |
3D structures mapped by conservation among orthologs
[ Domain: "Ribonuclease H-like" // Fumble_C ]
[ Domain: "Ribonuclease H-like" // Fumble_N ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3410246 |  |
IC50 | = | 70.0 | nM | 391.5 | CSc1cccc(NC(=O)CCc2c(C)nc3c4cccnc4nn3c2C)c1 | Homo sapiens | CHEMBL3413787 | single protein format |
| CHEMBL3410398 |  |
IC50 | = | 190.0 | nM | 413.4 | Cc1nc2c3cccnc3nn2c(C)c1CCC(=O)Nc1cccc(C(F)(F)F)c1 | Homo sapiens | CHEMBL3413790 | single protein format |
| CHEMBL3410256 |  |
IC50 | = | 240.0 | nM | 363.4 | Cc1nc2c3cccnc3nn2c(C)c1CCC(=O)Nc1cccc(F)c1 | Homo sapiens | CHEMBL3413790 | single protein format |
| CHEMBL1555019 |  |
IC50 | = | 280.0 | nM | 375.43 | COc1cccc(NC(=O)CCc2c(C)nc3c4cccnc4nn3c2C)c1 | Homo sapiens | CHEMBL3413790 | single protein format |
| CHEMBL3410257 |  |
IC50 | = | 550.0 | nM | 363.4 | Cc1nc2c3cccnc3nn2c(C)c1CCC(=O)Nc1ccccc1F | Homo sapiens | CHEMBL3413790 | single protein format |
| CHEMBL3410400 |  |
IC50 | = | 640.0 | nM | 402.46 | CC(=O)Nc1ccc(NC(=O)CCc2c(C)nc3c4cccnc4nn3c2C)cc1 | Homo sapiens | CHEMBL3413790 | single protein format |
| CHEMBL3410249 |  |
IC50 | = | 850.0 | nM | 345.41 | Cc1nc2c3cccnc3nn2c(C)c1CCC(=O)Nc1ccccc1 | Homo sapiens | CHEMBL3413790 | single protein format |