Q8TDU6 | GPBAR_HUMAN | G-protein coupled bile acid receptor 1 (GPBAR1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 - 7 transmembrane receptor (rhodopsin family) | 32~249 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3234568 |  |
IC50 | = | 90.0 | nM | 501.56 | CN1CCN(c2cc(N3CCC[C@@H](C(=O)NCCc4ccc(C#N)cc4)C3)nc(C(F)(F)F)n2)CC1 | Homo sapiens | CHEMBL3239427 | single protein format |
| CHEMBL3234871 |  |
IC50 | = | 215.0 | nM | 577.61 | N#Cc1ccc(CCNC(=O)[C@@H]2CCN2c2cc(-c3ccc([C@H]4CC[C@H](C(=O)O)CC4)cc3)nc(C(F)(F)F)n2)cc1 | Homo sapiens | CHEMBL3239427 | single protein format |
| CHEMBL131 |  |
IC50 | = | 251.0 | nM | 360.45 | C[C@]12C=CC(=O)C=C1CC[C@@H]1[C@@H]2[C@@H](O)C[C@@]2(C)[C@H]1CC[C@]2(O)C(=O)CO | Homo sapiens | CHEMBL3796546 | tissue-based format |