Q8TCT1 | PHOP1_HUMAN | Phosphoethanolamine/phosphocholine phosphatase (PHOSPHO1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF06888 | Put_Phosphatase - Putative Phosphatase | 28~263 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL1732623 |  |
IC50 | = | 23.3 | nM | 335.27 | O=c1c2c([N+](=O)[O-])cc([N+](=O)[O-])cc2sn1-c1ccccc1F | Homo sapiens | CHEMBL1738189 | single protein format |
| CHEMBL1724427 |  |
IC50 | = | 34.8 | nM | 335.27 | O=c1c2c([N+](=O)[O-])cc([N+](=O)[O-])cc2sn1-c1cccc(F)c1 | Homo sapiens | CHEMBL1738189 | single protein format |
| CHEMBL1606007 |  |
IC50 | = | 72.5 | nM | 396.18 | O=c1c2c([N+](=O)[O-])cc([N+](=O)[O-])cc2sn1-c1ccc(Br)cc1 | Homo sapiens | CHEMBL1738189 | single protein format |
| CHEMBL1714665 |  |
IC50 | = | 100.0 | nM | 335.27 | O=c1c2c([N+](=O)[O-])cc([N+](=O)[O-])cc2sn1-c1ccc(F)cc1 | Homo sapiens | CHEMBL1738189 | single protein format |
| CHEMBL51085 |  |
IC50 | = | 111.0 | nM | 274.18 | O=c1c2ccccc2[se]n1-c1ccccc1 | Homo sapiens | CHEMBL1738189 | single protein format |
| CHEMBL1570441 |  |
IC50 | = | 139.0 | nM | 298.37 | CN(C)C(=O)c1cccc(-n2sc3ccccc3c2=O)c1 | Homo sapiens | CHEMBL1738189 | single protein format |
| CHEMBL1725457 |  |
IC50 | = | 192.5 | nM | 369.72 | O=c1c2c([N+](=O)[O-])cc([N+](=O)[O-])cc2sn1-c1ccc(F)c(Cl)c1 | Homo sapiens | CHEMBL1738189 | single protein format |
| CHEMBL1717022 |  |
IC50 | = | 233.0 | nM | 417.73 | O=c1c2c([N+](=O)[O-])cc([N+](=O)[O-])cc2sn1-c1ccc(OC(F)(F)Cl)cc1 | Homo sapiens | CHEMBL1738189 | single protein format |
| CHEMBL1727796 |  |
IC50 | = | 252.0 | nM | 374.73 | O=c1c2ccc([N+](=O)[O-])cc2sn1-c1cc(C(F)(F)F)ccc1Cl | Homo sapiens | CHEMBL1738189 | single protein format |
| CHEMBL1705022 |  |
IC50 | = | 359.0 | nM | 314.17 | O=c1c2ccc(F)cc2sn1-c1cccc(Cl)c1Cl | Homo sapiens | CHEMBL1738189 | single protein format |
| CHEMBL1733472 |  |
IC50 | = | 384.5 | nM | 314.17 | O=c1c2ccc(F)cc2sn1-c1cc(Cl)ccc1Cl | Homo sapiens | CHEMBL1738189 | single protein format |
| CHEMBL480 |  |
IC50 | = | 434.0 | nM | 369.37 | Cc1c(OCC(F)(F)F)ccnc1C[S+]([O-])c1nc2ccccc2[nH]1 | Homo sapiens | CHEMBL1738189 | single protein format |
| CHEMBL1392315 |  |
IC50 | = | 489.0 | nM | 360.46 | O=c1c2ccccc2sn1-c1ccc(S(=O)(=O)N2CCCC2)cc1 | Homo sapiens | CHEMBL1738189 | single protein format |
| CHEMBL1339149 |  |
IC50 | = | 495.0 | nM | 334.42 | CN(C)S(=O)(=O)c1cccc(-n2sc3ccccc3c2=O)c1 | Homo sapiens | CHEMBL1738189 | single protein format |
| CHEMBL1731467 |  |
IC50 | = | 497.5 | nM | 313.3 | [N-]=[N+]=Nc1cc([N+](=O)[O-])cc2sn(-c3ccccc3)c(=O)c12 | Homo sapiens | CHEMBL1738189 | single protein format |
| CHEMBL1734915 |  |
IC50 | = | 534.0 | nM | 314.17 | O=c1c2ccc(F)cc2sn1-c1ccc(Cl)cc1Cl | Homo sapiens | CHEMBL1738189 | single protein format |
| CHEMBL1728593 |  |
IC50 | = | 545.0 | nM | 376.46 | O=c1c2ccccc2sn1-c1ccc(S(=O)(=O)N2CCOCC2)cc1 | Homo sapiens | CHEMBL1738189 | single protein format |
| CHEMBL1726776 |  |
IC50 | = | 555.0 | nM | 418.78 | Cc1c(Cl)cccc1-n1sc2cc([N+](=O)[O-])cc(OCC(F)(F)F)c2c1=O | Homo sapiens | CHEMBL1738189 | single protein format |
| CHEMBL1713178 |  |
IC50 | = | 555.3 | nM | 362.48 | CCN(CC)S(=O)(=O)c1cccc(-n2sc3ccccc3c2=O)c1 | Homo sapiens | CHEMBL1738189 | single protein format |
| CHEMBL1722737 |  |
IC50 | = | 563.5 | nM | 348.61 | O=c1c2ccc(F)cc2sn1-c1cc(Cl)c(Cl)cc1Cl | Homo sapiens | CHEMBL1738189 | single protein format |