Q8NHU3 | SMS2_HUMAN | Phosphatidylcholine:ceramide cholinephosphotransferase 2 (SGMS2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF14360 | PAP2_C - PAP2 superfamily C-terminal | 221~293 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4203399 |  |
IC50 | = | 90.0 | nM | 386.24 | Clc1cccc(Cl)c1COc1cccc2onc(Nc3cccnc3)c12 | Homo sapiens | CHEMBL4200192 | single protein format |
| CHEMBL4204352 |  |
IC50 | = | 100.0 | nM | 369.78 | Fc1ccc(Cl)c(COc2cccc3onc(Nc4cccnc4)c23)c1 | Homo sapiens | CHEMBL4200192 | single protein format |
| CHEMBL4214637 |  |
IC50 | = | 100.0 | nM | 351.79 | Clc1cccc(COc2cccc3onc(Nc4cccnc4)c23)c1 | Homo sapiens | CHEMBL4200192 | single protein format |
| CHEMBL4207944 |  |
IC50 | = | 110.0 | nM | 401.34 | FC(F)(F)Oc1ccccc1COc1cccc2onc(Nc3cccnc3)c12 | Homo sapiens | CHEMBL4200192 | single protein format |
| CHEMBL4634669 |  |
IC50 | = | 120.0 | nM | 568.44 | CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1c(OCCCC(F)(F)F)c2ccccc2n(C)c1=O | Homo sapiens | CHEMBL4628266 | cell-based format |
| CHEMBL4202436 |  |
IC50 | = | 150.0 | nM | 345.4 | Cc1cccc(C)c1COc1cccc2onc(Nc3cccnc3)c12 | Homo sapiens | CHEMBL4200192 | single protein format |
| CHEMBL4206801 |  |
IC50 | = | 160.0 | nM | 335.34 | Fc1cccc(COc2cccc3onc(Nc4cccnc4)c23)c1 | Homo sapiens | CHEMBL4200192 | single protein format |
| CHEMBL4205965 |  |
IC50 | = | 190.0 | nM | 331.38 | Cc1cccc(COc2cccc3onc(Nc4cccnc4)c23)c1 | Homo sapiens | CHEMBL4200192 | single protein format |
| CHEMBL4634697 |  |
IC50 | = | 210.0 | nM | 576.54 | CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1c(OCCCc2ccccc2)c2ccccc2n(C)c1=O | Homo sapiens | CHEMBL4628266 | cell-based format |
| CHEMBL4217275 |  |
IC50 | = | 240.0 | nM | 345.4 | CCc1ccccc1COc1cccc2onc(Nc3cccnc3)c12 | Homo sapiens | CHEMBL4200192 | single protein format |
| CHEMBL4211357 |  |
IC50 | = | 240.0 | nM | 347.37 | COc1ccccc1COc1cccc2onc(Nc3cccnc3)c12 | Homo sapiens | CHEMBL4200192 | single protein format |
| CHEMBL4202973 |  |
IC50 | = | 270.0 | nM | 351.79 | Clc1ccccc1COc1cccc2onc(Nc3cccnc3)c12 | Homo sapiens | CHEMBL4200192 | single protein format |
| CHEMBL4212291 |  |
IC50 | = | 340.0 | nM | 317.35 | c1ccc(COc2cccc3onc(Nc4cccnc4)c23)cc1 | Homo sapiens | CHEMBL4200192 | single protein format |
| CHEMBL4637599 |  |
IC50 | = | 350.0 | nM | 528.49 | CC(C)CCOc1c(C(=O)N(C)Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c(=O)n(C)c2ccccc12 | Homo sapiens | CHEMBL4628266 | cell-based format |
| CHEMBL4649105 |  |
IC50 | = | 380.0 | nM | 592.54 | CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1c(OCCOCc2ccccc2)c2ccccc2n(C)c1=O | Homo sapiens | CHEMBL4628266 | cell-based format |
| CHEMBL4544787 |  |
IC50 | = | 430.0 | nM | 452.98 | CCCCCCCOc1ccc(Cl)cc1COc1ccccc1C(=O)Nc1cccnc1 | Homo sapiens | CHEMBL4412720 | subcellular format |
| CHEMBL4162182 |  |
IC50 | = | 470.0 | nM | 511.47 | CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1c(N2CCCC2)c2ccccc2n(C)c1=O | Homo sapiens | CHEMBL4139289 | cell-based format |
| CHEMBL4472866 |  |
IC50 | = | 470.0 | nM | 438.96 | O=C(Nc1cccnc1)c1ccccc1OCc1ccccc1OCCCCCCCl | Homo sapiens | CHEMBL4412720 | subcellular format |
| CHEMBL4217676 |  |
IC50 | = | 470.0 | nM | 331.38 | Cc1ccccc1COc1cccc2onc(Nc3cccnc3)c12 | Homo sapiens | CHEMBL4200192 | single protein format |
| CHEMBL4638097 |  |
IC50 | = | 480.0 | nM | 582.58 | CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1c(OCCCC2CCCCC2)c2ccccc2n(C)c1=O | Homo sapiens | CHEMBL4628266 | cell-based format |