Q8NB78 | KDM1B_HUMAN | Lysine-specific histone demethylase 1B (KDM1B)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01593 | Amino_oxidase | 393–819 | |
| PF04433 | SWIRM | 292–363 | |
| PF07496 | zf-CW | 138–190 |
3D structures mapped by conservation among orthologs
[ Domain: "tri-helical" // SWIRM ]
[ Domain: "FAD-linked reductases-C" // Amino_oxidase_2nd ]
[ Domain: "FAD/NAD(P)-binding domain" // Amino_oxidase_1st ]
[ Domain: "FYVE/PHD zinc finger" // zf-CW ]
[ Domain: "C4H2C2-type zinc finger" // zf-C3HC4_4 ]
[ Domain: "C4H2C2-type zinc finger" // UNK_F_TYPE ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5206450 |  |
IC50 | = | 600.0 | nM | 425.6 | CC1(CNC2CC2c2ccc3c(c2)CCN3S(=O)(=O)c2ccccc2)CCNCC1 | Homo sapiens | CHEMBL5159713 | single protein format |
| CHEMBL5191047 |  |
IC50 | = | 760.0 | nM | 461.63 | O=S(=O)(c1ccc2ccccc2c1)N1CCc2cc(C3CC3NCC3CCNCC3)ccc21 | Homo sapiens | CHEMBL5159713 | single protein format |
| CHEMBL5205837 |  |
IC50 | = | 800.0 | nM | 487.67 | O=S(=O)(c1ccc(-c2ccccc2)cc1)N1CCc2cc(C3CC3NCC3CCNCC3)ccc21 | Homo sapiens | CHEMBL5159713 | single protein format |