Q8N3A8 | PARP8_HUMAN | Protein mono-ADP-ribosyltransferase PARP8 (PARP8)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00644 | PARP | 680–752 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5403305 |  |
IC50 | = | 13.0 | nM | 488.5 | CCC(CC)N1CCN(C(=O)c2cc(Cn3c(=O)[n-]c(=O)c4ccccc43)ccc2F)CC1=O.[Na+] | Homo sapiens | CHEMBL5373896 | single protein format |
| CHEMBL521686 |  |
IC50 | = | 240.0 | nM | 434.47 | O=C(c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F)N1CCN(C(=O)C2CC2)CC1 | Homo sapiens | CHEMBL5373896 | single protein format |