Q8IVW4 | CDKL3_HUMAN | Cyclin-dependent kinase-like 3 (CDKL3)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 4~286 |
3D structures mapped by conservation among orthologs
[ Domain: "Protein kinase" // Pkinase_Tyr ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5426285 |  |
IC50 | = | 0.5 | nM | 358.47 | COC[C@@H](CC(C)C)NC1=N/C(=C\c2ccc3ncsc3c2)C(=O)N1 | Homo sapiens | CHEMBL5378503 | single protein format |
| CHEMBL574738 |  |
IC50 | = | 7.1 | nM | 529.57 | CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 | Homo sapiens | CHEMBL4739035 | single protein format |
| CHEMBL5190023 |  |
IC50 | = | 143.0 | nM | 527.45 | CNC(=O)[C@]1(C)CC[C@@H](Nc2ncc3c(Br)nn(-c4ccc(-c5nnc(C)s5)cc4)c3n2)C1 | Homo sapiens | CHEMBL5111594 | single protein format |
| CHEMBL5393904 |  |
IC50 | = | 668.5 | nM | 542.85 | O=C(c1cccc(CNc2n[nH]c3cccc(Cl)c23)c1)N1CCN(C(=O)c2ccc(Cl)cc2Cl)CC1 | Homo sapiens | CHEMBL5318991 | single protein format |