Q7Z6Z7 | HUWE1_HUMAN | E3 ubiquitin-protein ligase HUWE1 (HUWE1)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00632 | HECT | 4068–4373 | |
| PF02825 | WWE | 1617–1678 | |
| PF06012 | DUF908 | 91–367 | |
| PF06025 | DUF913 | 430–814 | |
| PF14377 | UBM | 2960–2991 | |
| PF14377 | UBM | 3011–3043 | |
| PF14377 | UBM | 3049–3082 | |
| PF22562 | UBA_7 | 1318–1356 |
3D structures mapped by conservation among orthologs
[ Domain: "WWE domain" // WWE ]
[ Domain: "RuvA-C, UBA, CRAL/TRIO-N, HBS1" // UBA ]
[ Domain: "Hect, E3 ligase catalytic domain" // HECT ]
[ Domain: "Ubiquitin-binding motif (UBM)" // DUF4414 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|