Q7L7X3 | TAOK1_HUMAN | Serine/threonine-protein kinase TAO1 (TAOK1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 29~280 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL388978 |  |
IC50 | = | 1.21 | nM | 466.54 | CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 | Homo sapiens | CHEMBL4328625 | single protein format |
| CHEMBL5409039 |  |
IC50 | = | 20.0 | nM | 539.64 | CC(C)(O)Cn1cc(-c2cnc3nc2N[C@H](CO)c2ccccc2OCCCCc2cc(ccc2C#N)N3)cn1 | Homo sapiens | CHEMBL5317039 | single protein format |
| CHEMBL2334586 |  |
IC50 | = | 20.0 | nM | 332.41 | CC(C)(O)C#Cc1ccc2[nH]c3c(c2c1)-c1nc(N)ncc1CCC3 | Homo sapiens | CHEMBL5111448 | assay format |
| CHEMBL3715987 |  |
IC50 | = | 50.0 | nM | 452.52 | O=C(NC(C(=O)NC1CCCc2ccccc21)c1cccnc1)c1ccc(-n2cncn2)cc1 | Homo sapiens | CHEMBL3720849 | assay format |
| CHEMBL3715380 |  |
IC50 | = | 50.0 | nM | 467.61 | O=C(NC1CCCc2ccccc21)C(NC(=O)C(c1ccccc1)C1CCCC1)c1cccnc1 | Homo sapiens | CHEMBL3720849 | assay format |
| CHEMBL3715872 |  |
IC50 | = | 50.0 | nM | 422.57 | CCCCCCCOc1ccc(C(=O)NCC(=O)NC2CCCc3ccccc32)cc1 | Homo sapiens | CHEMBL3720849 | assay format |
| CHEMBL3716788 |  |
IC50 | = | 50.0 | nM | 408.54 | CCCCCOc1ccc(C(=O)NC(C)C(=O)NC2CCc3ccccc3C2)cc1 | Homo sapiens | CHEMBL3720849 | assay format |
| CHEMBL3717287 |  |
IC50 | = | 50.0 | nM | 392.54 | CCCCCCc1ccc(C(=O)NCC(=O)NC2CCCc3ccccc32)cc1 | Homo sapiens | CHEMBL3720849 | assay format |
| CHEMBL3717391 |  |
IC50 | = | 50.0 | nM | 378.52 | CCCCCc1ccc(C(=O)NCC(=O)NC2CCCc3ccccc32)cc1 | Homo sapiens | CHEMBL3720849 | assay format |
| CHEMBL3717236 |  |
IC50 | = | 50.0 | nM | 538.65 | COc1cc2c(cc1OC)NC(C(=O)N[C@@H](Cc1c[nH]c3ccccc13)C(=O)NC1CCCc3ccccc31)C2 | Homo sapiens | CHEMBL3720849 | assay format |
| CHEMBL3715148 |  |
IC50 | = | 50.0 | nM | 417.3 | O=C(COc1ccc(Br)cc1)NCC(=O)NC1CCCc2ccccc21 | Homo sapiens | CHEMBL3720849 | assay format |
| CHEMBL3715806 |  |
IC50 | = | 50.0 | nM | 509.65 | CCCCOc1ccc(C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)NC2CCCc3ccccc32)cc1 | Homo sapiens | CHEMBL3720849 | assay format |
| CHEMBL3718397 |  |
IC50 | = | 50.0 | nM | 494.98 | COc1ccc(/C=C/C(=O)N2Cc3[nH]cnc3CC2C(=O)NCCc2cccc(Cl)c2)cc1OC | Homo sapiens | CHEMBL3720849 | assay format |
| CHEMBL3717998 |  |
IC50 | < | 50.0 | nM | 489.55 | COc1ccc2nc(NC(=O)COC(=O)CC(NC(=O)c3ccccc3)c3ccccc3)sc2c1 | Homo sapiens | CHEMBL3720849 | assay format |
| CHEMBL3717452 |  |
IC50 | = | 50.0 | nM | 523.63 | COc1ccc(/C=C/C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)NC2CCCc3ccccc32)cc1OC | Homo sapiens | CHEMBL3720849 | assay format |
| CHEMBL3716597 |  |
IC50 | = | 50.0 | nM | 406.57 | CCCCCCCc1ccc(C(=O)NCC(=O)NC2CCCc3ccccc32)cc1 | Homo sapiens | CHEMBL3720849 | assay format |
| CHEMBL3715887 |  |
IC50 | = | 50.0 | nM | 444.53 | O=C(COc1ccc(OCc2ccccc2)cc1)NCC(=O)NC1CCCc2ccccc21 | Homo sapiens | CHEMBL3720849 | assay format |
| CHEMBL3717424 |  |
IC50 | = | 50.0 | nM | 474.54 | O=C(CC(NC(=O)c1ccccc1)c1ccccc1)NCC(=O)Nc1nc2ccc(O)cc2s1 | Homo sapiens | CHEMBL3720849 | assay format |
| CHEMBL3716744 |  |
IC50 | = | 50.0 | nM | 394.52 | CCCCOc1ccc(C(=O)NC(C)C(=O)NC2CCc3ccccc3C2)cc1 | Homo sapiens | CHEMBL3720849 | assay format |
| CHEMBL3717017 |  |
IC50 | = | 50.0 | nM | 394.52 | CCCCCOc1ccc(C(=O)NCC(=O)NC2CCCc3ccccc32)cc1 | Homo sapiens | CHEMBL3720851 | assay format |