Q70CQ3 | UBP30_HUMAN | Ubiquitin carboxyl-terminal hydrolase 30 (USP30)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00443 | UCH - Ubiquitin carboxyl-terminal hydrolase | 69~499 |
3D structures mapped by conservation among orthologs
[ Domain: "Cysteine proteinases" // UCH ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4584791 |  |
IC50 | = | 1.0 | nM | 321.34 | N#Cc1cccc(-c2cc(NC(=O)C[C@H]3CCN(C#N)C3)no2)c1 | Homo sapiens | CHEMBL4418459 | assay format |
| CHEMBL4544816 |  |
IC50 | = | 1.0 | nM | 332.37 | N#Cc1ccnc(-c2ccc(N3CCO[C@H]4CN(C#N)C[C@H]43)nc2)c1 | Homo sapiens | CHEMBL4418460 | assay format |
| CHEMBL4525477 |  |
IC50 | = | 1.0 | nM | 332.37 | N#Cc1cccc(-c2cnc(N3CCO[C@H]4CN(C#N)C[C@H]43)cn2)c1 | Homo sapiens | CHEMBL4418460 | assay format |
| CHEMBL4467425 |  |
IC50 | = | 1.0 | nM | 332.37 | N#Cc1cccc(-c2cnc(N3CCO[C@H]4CN(C#N)C[C@H]43)nc2)c1 | Homo sapiens | CHEMBL4418460 | assay format |
| CHEMBL4455275 |  |
IC50 | = | 1.0 | nM | 331.38 | N#Cc1cccc(-c2ccc(N3CCO[C@H]4CN(C#N)C[C@H]43)nc2)c1 | Homo sapiens | CHEMBL4418460 | assay format |
| CHEMBL4559084 |  |
IC50 | = | 1.0 | nM | 332.37 | N#Cc1cc(-c2ccc(N3CCO[C@@H]4CN(C#N)C[C@@H]43)nc2)ccn1 | Homo sapiens | CHEMBL4418460 | assay format |
| CHEMBL4565384 |  |
IC50 | = | 1.0 | nM | 330.77 | N#CN1CC[C@H](CC(=O)Nc2cc(-c3cccc(Cl)c3)no2)C1 | Homo sapiens | CHEMBL4418459 | assay format |
| CHEMBL4474904 |  |
IC50 | = | 1.0 | nM | 344.8 | C[C@H](C(=O)Nc1cc(-c2cccc(Cl)c2)no1)[C@@H]1CCN(C#N)C1 | Homo sapiens | CHEMBL4418459 | assay format |
| CHEMBL4541601 |  |
IC50 | = | 1.0 | nM | 380.33 | N#CN1CC[C@H](CC(=O)Nc2cc(-c3cccc(OC(F)(F)F)c3)no2)C1 | Homo sapiens | CHEMBL4418459 | assay format |
| CHEMBL4443477 |  |
IC50 | = | 1.0 | nM | 321.34 | N#Cc1cccc(-c2cc(NC(=O)C[C@H]3CCN(C#N)C3)on2)c1 | Homo sapiens | CHEMBL4418459 | assay format |
| CHEMBL4460685 |  |
IC50 | = | 10.0 | nM | 299.37 | COc1ccc(C2CN(C(=O)C[C@@H]3CCN(C#N)C3)C2)cc1 | Homo sapiens | CHEMBL4418459 | assay format |
| CHEMBL4444321 |  |
IC50 | = | 10.0 | nM | 365.44 | COc1ccc(C2CN(C(=O)C[C@@H]3CCN(C#N)C3)C2)cc1-c1ccn[nH]1 | Homo sapiens | CHEMBL4418459 | assay format |
| CHEMBL4445598 |  |
IC50 | = | 10.0 | nM | 379.46 | COc1ccc(C2CN(C(=O)C[C@@H]3CCN(C#N)C3)C2)cc1-c1ccnn1C | Homo sapiens | CHEMBL4418459 | assay format |
| CHEMBL4459110 |  |
IC50 | = | 10.0 | nM | 330.77 | N#CN1CC[C@@H](CC(=O)Nc2cc(-c3cccc(Cl)c3)no2)C1 | Homo sapiens | CHEMBL4418459 | assay format |
| CHEMBL4444397 |  |
IC50 | = | 10.0 | nM | 326.36 | COc1cccc(-c2cc(NC(=O)C[C@H]3CCN(C#N)C3)on2)c1 | Homo sapiens | CHEMBL4418459 | assay format |
| CHEMBL4538624 |  |
IC50 | = | 10.0 | nM | 379.46 | COc1ccc(C2CN(C(=O)C[C@@H]3CCN(C#N)C3)C2)cc1-c1cnn(C)c1 | Homo sapiens | CHEMBL4418459 | assay format |
| CHEMBL4467362 |  |
IC50 | = | 10.0 | nM | 308.39 | Cc1cc(C2CN(C(=O)C[C@@H]3CCN(C#N)C3)C2)ccc1C#N | Homo sapiens | CHEMBL4418459 | assay format |
| CHEMBL4566816 |  |
IC50 | = | 10.0 | nM | 317.36 | COc1cccc(C2CN(C(=O)C[C@@H]3CCN(C#N)C3)C2)c1F | Homo sapiens | CHEMBL4418459 | assay format |
| CHEMBL4458543 |  |
IC50 | = | 10.0 | nM | 353.76 | N#CN1C[C@H]2CCN(c3nc4ccc(OC(F)(F)Cl)cc4[nH]3)[C@H]2C1 | Homo sapiens | CHEMBL4418460 | assay format |
| CHEMBL4459141 |  |
IC50 | = | 10.0 | nM | 332.37 | N#Cc1cc(-c2ccc(N3CCO[C@H]4CN(C#N)C[C@H]43)nc2)ccn1 | Homo sapiens | CHEMBL4418460 | assay format |