Q6SZW1 | SARM1_HUMAN | NAD(+) hydrolase SARM1 (SARM1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF07647 | SAM_2 - SAM domain (Sterile alpha motif) | 409~474 | |
| PF07647 | SAM_2 - SAM domain (Sterile alpha motif) | 480~545 | |
| PF13676 | TIR_2 - TIR domain | 564~680 |
3D structures mapped by conservation among orthologs
[ Domain: "SAM domain-like" // SAM_1 ]
[ Domain: "Toll/Interleukin receptor TIR domain" // TIR ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL2009370 |  |
IC50 | = | 150.0 | nM | 241.34 | CN(C)c1n/c(=N/Cc2ccco2)ss1 | Homo sapiens | CHEMBL4422590 | cell-based format |
| CHEMBL2004241 |  |
IC50 | < | 150.0 | nM | 322.25 | Br.CN(C)c1n/c(=N/Cc2ccco2)ss1 | Homo sapiens | CHEMBL4422580 | cell-based format |
| CHEMBL2009483 |  |
IC50 | = | 700.0 | nM | 271.8 | CN(C)c1n/c(=N/c2cccc(Cl)c2)ss1 | Homo sapiens | CHEMBL4422590 | cell-based format |