Q6PHR2 | ULK3_HUMAN | Serine/threonine-protein kinase ULK3 (ULK3)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 17~270 | |
| PF04212 | MIT - MIT (microtubule interacting and transport) domain | 281~345 | |
| PF04212 | MIT - MIT (microtubule interacting and transport) domain | 376~442 |
3D structures mapped by conservation among orthologs
[ Domain: "MIT domain" // MIT ]
[ Domain: "Protein kinase" // Pkinase_Tyr ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL388978 |  |
IC50 | = | 4.2 | nM | 466.54 | CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 | Homo sapiens | CHEMBL4328649 | single protein format |
| CHEMBL5079601 |  |
IC50 | = | 343.0 | nM | 451.5 | Cc1nn(CC(F)(F)F)cc1Nc1ncc(C2CC2)c(NCCCNC(=O)C2CCC2)n1 | Homo sapiens | CHEMBL5046606 | single protein format |
| CHEMBL4446892 |  |
IC50 | = | 946.0 | nM | 520.34 | Cc1nn(CC(F)(F)F)cc1Nc1ncc(Br)c(NCc2ccc(S(N)(=O)=O)cc2)n1 | Homo sapiens | CHEMBL5046606 | single protein format |