Q6PCB7 | S27A1_HUMAN | Long-chain fatty acid transport protein 1 (SLC27A1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00501 | AMP-binding - AMP-binding enzyme | 82~432 | |
| PF13193 | AMP-binding_C - AMP-binding enzyme C-terminal domain | 523~598 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL2377769 |  |
IC50 | = | 26.0 | nM | 388.51 | CC1CCc2sc(NC(=O)CN3CCN(c4ccc(F)cc4)CC3)nc2C1 | Homo sapiens | CHEMBL2378196 | single protein format |
| CHEMBL2377620 |  |
IC50 | = | 41.0 | nM | 389.5 | CN(C(=O)CN1CCN(c2ccc(F)cn2)CC1)c1nc2c(s1)CCCC2 | Homo sapiens | CHEMBL2378196 | single protein format |
| CHEMBL2377621 |  |
IC50 | = | 46.0 | nM | 375.47 | O=C(CN1CCN(c2ccc(F)cn2)CC1)Nc1nc2c(s1)CCCC2 | Homo sapiens | CHEMBL2378196 | single protein format |
| CHEMBL2377766 |  |
IC50 | = | 77.0 | nM | 374.49 | O=C(CN1CCN(c2ccc(F)cc2)CC1)Nc1nc2c(s1)CCCC2 | Homo sapiens | CHEMBL2378196 | single protein format |
| CHEMBL2377622 |  |
IC50 | = | 100.0 | nM | 359.41 | O=C(CN1CCN(c2ccc(F)cn2)CC1)Nc1nc2c(o1)CCCC2 | Homo sapiens | CHEMBL2378196 | single protein format |
| CHEMBL2377611 |  |
IC50 | = | 100.0 | nM | 343.41 | O=C(CN1CCN(c2ccc(F)cn2)CC1)c1cnc2n1CCCC2 | Homo sapiens | CHEMBL2378196 | single protein format |
| CHEMBL2058359 |  |
IC50 | = | 100.0 | nM | 449.46 | CCn1c(CNc2ccccc2)nnc1SCc1nc2cc(OC(F)(F)F)ccc2o1 | Homo sapiens | CHEMBL2061593 | single protein format |
| CHEMBL2377763 |  |
IC50 | = | 120.0 | nM | 388.51 | O=C(CN1CCN(c2ccc(F)cc2)CC1)Nc1nc2c(s1)CCCCC2 | Homo sapiens | CHEMBL2378196 | single protein format |
| CHEMBL2377617 |  |
IC50 | = | 130.0 | nM | 339.37 | O=C(CN1CCN(c2ccc(F)cn2)CC1)c1cnc2ccccn12 | Homo sapiens | CHEMBL2378196 | single protein format |
| CHEMBL2377764 |  |
IC50 | = | 180.0 | nM | 358.42 | O=C(CN1CCN(c2ccc(F)cc2)CC1)Nc1nc2c(o1)CCCC2 | Homo sapiens | CHEMBL2378196 | single protein format |
| CHEMBL2058343 |  |
IC50 | = | 190.0 | nM | 421.53 | CCC(=O)c1ccc2oc(CSc3nnc(CNc4ccccc4)n3CC)nc2c1 | Homo sapiens | CHEMBL2061593 | single protein format |
| CHEMBL2377610 |  |
IC50 | = | 190.0 | nM | 357.43 | Cc1nc2n(c1C(=O)CN1CCN(c3ccc(F)cn3)CC1)CCCC2 | Homo sapiens | CHEMBL2378196 | single protein format |
| CHEMBL2377757 |  |
IC50 | = | 200.0 | nM | 357.48 | O=C(CN1CCN(c2ccccn2)CC1)Nc1nc2c(s1)CCCC2 | Homo sapiens | CHEMBL2378196 | single protein format |
| CHEMBL2058092 |  |
IC50 | = | 230.0 | nM | 437.57 | CCCC(=O)c1ccc(NC(=O)CSc2nnc(CNc3ccccc3)n2CC)cc1 | Homo sapiens | CHEMBL2061593 | single protein format |
| CHEMBL2377761 |  |
IC50 | = | 250.0 | nM | 370.52 | Cc1ccc(N2CCN(CC(=O)Nc3nc4c(s3)CCCC4)CC2)cc1 | Homo sapiens | CHEMBL2378196 | single protein format |
| CHEMBL2058349 |  |
IC50 | = | 260.0 | nM | 436.54 | CC/C(=N/O)c1ccc2oc(CSc3nnc(CNc4ccccc4)n3CC)nc2c1 | Homo sapiens | CHEMBL2061593 | single protein format |
| CHEMBL2377760 |  |
IC50 | = | 280.0 | nM | 356.5 | O=C(CN1CCN(c2ccccc2)CC1)Nc1nc2c(s1)CCCC2 | Homo sapiens | CHEMBL2378196 | single protein format |
| CHEMBL2377614 |  |
IC50 | = | 330.0 | nM | 339.37 | O=C(CN1CCN(c2ccc(F)cn2)CC1)c1cnn2ccccc12 | Homo sapiens | CHEMBL2378196 | single protein format |
| CHEMBL2058076 |  |
IC50 | = | 330.0 | nM | 439.54 | CCOC(=O)c1ccc(NC(=O)CSc2nnc(CNc3ccccc3)n2CC)cc1 | Homo sapiens | CHEMBL2061593 | single protein format |
| CHEMBL2058358 |  |
IC50 | = | 360.0 | nM | 433.46 | CCn1c(CNc2ccccc2)nnc1SCc1nc2cc(C(F)(F)F)ccc2o1 | Homo sapiens | CHEMBL2061593 | single protein format |