Q6P2Q9 | PRP8_HUMAN | Pre-mRNA-processing-splicing factor 8 (PRPF8)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01398 | JAB | 2100–2204 | |
| PF08082 | PRO8NT | 58–209 | |
| PF08083 | PROCN | 396–801 | |
| PF08084 | PROCT | 2212–2332 | |
| PF10596 | U6-snRNA_bdg | 1442–1600 | |
| PF10597 | U5_2-snRNA_bdg | 1210–1343 | |
| PF10598 | RRM_4 | 986–1076 | |
| PF12134 | PRP8_domainIV | 1760–1988 |
3D structures mapped by conservation among orthologs
[ Domain: "helical bundle domain in reverse transcriptase-like polymerases" // U5_2-snRNA_bdg ]
[ Domain: "Pre-mRNA-splicing factor 8 N-terminal domain" // PROCN_C,PROCN_N ]
[ Domain: "Adenylyl and guanylyl cyclase catalytic domain-like" // RRM_4 ]
[ Domain: "Cytidine deaminase-like" // PROCT ]
[ Domain: "Restriction endonuclease-like" // U6-snRNA_bdg ]
[ Domain: "Ribonuclease H-like" // PRP8_domainIV ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
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