Q6P2M8 | KCC1B_HUMAN | Calcium/calmodulin-dependent protein kinase type 1B (PNCK)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 15~270 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4635883 |  |
IC50 | = | 3.0 | nM | 397.53 | CC(C)c1cc(Nc2nc(N3CCC[C@H](N)C3)ncc2C(N)=O)cc(C(C)C)n1 | Homo sapiens | CHEMBL4629895 | single protein format |
| CHEMBL388978 |  |
IC50 | = | 4.99 | nM | 466.54 | CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 | Homo sapiens | CHEMBL4328330 | single protein format |
| CHEMBL4640712 |  |
IC50 | = | 11.0 | nM | 446.56 | CC(C)(C#N)c1cc(Nc2nc(N3CCC[C@H](N)C3)ncc2C(N)=O)cc(C(C)(C)C#N)c1 | Homo sapiens | CHEMBL4629895 | single protein format |
| CHEMBL5093741 |  |
IC50 | = | 830.0 | nM | 468.44 | CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]cc(c3c2)-c2cn(nc2C(F)(F)F)CCCC1=O | Homo sapiens | CHEMBL5046158 | single protein format |