Q6P1M0 | S27A4_HUMAN | Long-chain fatty acid transport protein 4 (SLC27A4)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00501 | AMP-binding - AMP-binding enzyme | 81~404 | |
| PF13193 | AMP-binding_C - AMP-binding enzyme C-terminal domain | 520~595 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL209855 |  |
IC50 | = | 90.0 | nM | 373.41 | CCCC/C=C/COC(=O)C1=C(C)NC(=O)NC1c1ccc([N+](=O)[O-])cc1 | Homo sapiens | CHEMBL870441 | cell-based format |
| CHEMBL211612 |  |
IC50 | = | 150.0 | nM | 387.44 | CC[C@H]1CC[C@H](OC(=O)C2=C(C)NC(=O)NC2c2ccc([N+](=O)[O-])cc2)CC1 | Homo sapiens | CHEMBL870441 | cell-based format |
| CHEMBL426323 |  |
IC50 | = | 180.0 | nM | 357.37 | CC1=C(C(=O)OC2C=CCCC2)C(c2ccc([N+](=O)[O-])cc2)NC(=O)N1 | Homo sapiens | CHEMBL870441 | cell-based format |
| CHEMBL211941 |  |
IC50 | = | 200.0 | nM | 345.36 | CC1=C(C(=O)OC2CCCC2)[C@H](c2ccc([N+](=O)[O-])cc2)NC(=O)N1 | Homo sapiens | CHEMBL870441 | cell-based format |
| CHEMBL211864 |  |
IC50 | = | 250.0 | nM | 345.36 | CC1=C(C(=O)OC2CCCC2)C(c2ccc([N+](=O)[O-])cc2)NC(=O)N1 | Homo sapiens | CHEMBL870441 | cell-based format |
| CHEMBL211117 |  |
IC50 | = | 260.0 | nM | 359.38 | CCC/C=C/COC(=O)C1=C(C)NC(=O)NC1c1ccc([N+](=O)[O-])cc1 | Homo sapiens | CHEMBL870441 | cell-based format |
| CHEMBL437303 |  |
IC50 | = | 500.0 | nM | 359.38 | CC1=C(C(=O)OC2CCCCC2)C(c2ccc([N+](=O)[O-])cc2)NC(=O)N1 | Homo sapiens | CHEMBL870441 | cell-based format |
| CHEMBL212149 |  |
IC50 | = | 600.0 | nM | 368.36 | CC1=C(C(=O)OC2CCCC2)[C@H](c2ccc(C(F)(F)F)cc2)NC(=O)N1 | Homo sapiens | CHEMBL870441 | cell-based format |
| CHEMBL378290 |  |
IC50 | = | 640.0 | nM | 345.36 | CC/C=C/COC(=O)C1=C(C)NC(=O)NC1c1ccc([N+](=O)[O-])cc1 | Homo sapiens | CHEMBL870441 | cell-based format |
| CHEMBL211772 |  |
IC50 | = | 650.0 | nM | 331.33 | C/C=C/COC(=O)C1=C(C)NC(=O)NC1c1ccc([N+](=O)[O-])cc1 | Homo sapiens | CHEMBL870441 | cell-based format |
| CHEMBL212012 |  |
IC50 | = | 700.0 | nM | 345.36 | CC/C=C\COC(=O)C1=C(C)NC(=O)NC1c1ccc([N+](=O)[O-])cc1 | Homo sapiens | CHEMBL870441 | cell-based format |
| CHEMBL211656 |  |
IC50 | = | 1000.0 | nM | 368.36 | CC1=C(C(=O)OC2CCCC2)C(c2ccc(C(F)(F)F)cc2)NC(=O)N1 | Homo sapiens | CHEMBL870441 | cell-based format |
| CHEMBL211182 |  |
IC50 | = | 1000.0 | nM | 379.25 | CC1=C(C(=O)OC2CCCC2)C(c2ccc(Br)cc2)NC(=O)N1 | Homo sapiens | CHEMBL870441 | cell-based format |
| CHEMBL208649 |  |
IC50 | = | 1000.0 | nM | 334.8 | CC1=C(C(=O)OC2CCCC2)C(c2ccc(Cl)cc2)NC(=O)N1 | Homo sapiens | CHEMBL870441 | cell-based format |