Q6L8Q7 | PDE12_HUMAN | 2',5'-phosphodiesterase 12 (PDE12)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF03372 | Exo_endo_phos | 299–599 | |
| PF21171 | PDE12-like_N | 161–271 |
3D structures mapped by conservation among orthologs
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // PLN03144_like ]
[ Domain: "DNase I-like" // Exo_endo_phos ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5415518 |  |
Ki | = | 17.5 | nM | 491.55 | Cn1c(-c2c[nH]c3cc(C#N)ccc23)nc2ccc(C(=O)N3CCOC(c4ccccc4)C3CO)cc21 | Homo sapiens | CHEMBL5326179 | single protein format |