Q6IQ55 | TTBK2_HUMAN | Tau-tubulin kinase 2 (TTBK2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 22~241 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5283456 |  |
IC50 | = | 1.4 | nM | 307.36 | CC[C@](C)(O)C#Cc1cc2c(ccn2-c2ccnc(N)n2)cn1 | Homo sapiens | CHEMBL5236887 | single protein format |
| CHEMBL5280210 |  |
IC50 | = | 1.6 | nM | 337.38 | CC[C@](C)(O)C#Cc1cc2c(ccn2-c2cc(OC)nc(N)n2)cn1 | Homo sapiens | CHEMBL5236887 | single protein format |
| CHEMBL5182036 |  |
IC50 | = | 2.7 | nM | 337.38 | CC[C@@](C)(O)C#Cc1cc2c(ccn2-c2cc(OC)nc(N)n2)cn1 | Homo sapiens | CHEMBL5156815 | single protein format |
| CHEMBL5273263 |  |
IC50 | = | 13.0 | nM | 308.35 | CC[C@](C)(O)C#Cc1cc2c(cn1)cnn2-c1ccnc(N)n1 | Homo sapiens | CHEMBL5236887 | single protein format |
| CHEMBL4528881 |  |
IC50 | = | 170.0 | nM | 431.34 | CC1(N)CCC(Nc2ccn3ncnc(Nc4cc(O)cc(Br)c4)c23)CC1 | Homo sapiens | CHEMBL4326706 | single protein format |
| CHEMBL5193906 |  |
IC50 | = | 170.0 | nM | 431.34 | CC1(N)CCN(Cc2ccn3ncnc(Nc4cc(O)cc(Br)c4)c23)CC1 | Homo sapiens | CHEMBL5156815 | single protein format |
| CHEMBL5200069 |  |
IC50 | = | 490.0 | nM | 336.78 | Clc1ccccc1Oc1ccc(Nc2ncnc3[nH]ccc23)cc1 | Homo sapiens | CHEMBL5156820 | single protein format |
| CHEMBL5198544 |  |
IC50 | = | 850.0 | nM | 302.34 | c1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 | Homo sapiens | CHEMBL5156820 | single protein format |
| CHEMBL5193488 |  |
IC50 | = | 970.0 | nM | 332.36 | COc1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 | Homo sapiens | CHEMBL5156820 | single protein format |