Q6DWJ6 | GP139_HUMAN | Probable G-protein coupled receptor 139 (GPR139)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 - 7 transmembrane receptor (rhodopsin family) | 44~285 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4777495 |  |
Ki | = | 10.0 | nM | 350.42 | Cc1ccc([C@H](C)NC(=O)Cn2nnc3c(C)cc(C)cc3c2=O)cc1 | Homo sapiens | CHEMBL4742408 | cell membrane format |
| CHEMBL4799483 |  |
Ki | = | 11.0 | nM | 424.35 | COc1cccc2nnn(CC(=O)N[C@@H](C)c3ccc(C(F)(F)F)cc3F)c(=O)c12 | Homo sapiens | CHEMBL4742408 | cell membrane format |
| CHEMBL4789720 |  |
Ki | = | 26.0 | nM | 406.36 | COc1cccc2nnn(CC(=O)N[C@@H](C)c3ccc(C(F)(F)F)cc3)c(=O)c12 | Homo sapiens | CHEMBL4742408 | cell membrane format |
| CHEMBL4780038 |  |
Ki | = | 26.0 | nM | 391.26 | Cc1ccc([C@H](C)NC(=O)Cn2nnc3c(Cl)cc(Cl)cc3c2=O)cc1 | Homo sapiens | CHEMBL4742408 | cell membrane format |
| CHEMBL4782204 |  |
Ki | = | 33.0 | nM | 440.35 | COc1cccc2nnn(CC(=O)N[C@@H](C)c3ccc(OC(F)(F)F)cc3F)c(=O)c12 | Homo sapiens | CHEMBL4742408 | cell membrane format |
| CHEMBL4796493 |  |
Ki | = | 33.0 | nM | 422.36 | COc1cccc2nnn(CC(=O)N[C@@H](C)c3ccc(OC(F)(F)F)cc3)c(=O)c12 | Homo sapiens | CHEMBL4742408 | cell membrane format |
| CHEMBL4776329 |  |
Ki | = | 39.0 | nM | 354.39 | Cc1ccc([C@H](C)NC(=O)Cn2nnc3ccc(F)cc3c2=O)c(C)c1 | Homo sapiens | CHEMBL4742408 | cell membrane format |
| CHEMBL4776988 |  |
Ki | = | 42.0 | nM | 410.33 | C[C@H](NC(=O)Cn1nnc2ccc(F)cc2c1=O)c1ccc(OC(F)(F)F)cc1 | Homo sapiens | CHEMBL4742408 | cell membrane format |
| CHEMBL4778172 |  |
Ki | = | 48.0 | nM | 352.39 | COc1cccc2nnn(CC(=O)N[C@@H](C)c3ccc(C)cc3)c(=O)c12 | Homo sapiens | CHEMBL4742408 | cell membrane format |
| CHEMBL4780801 |  |
Ki | = | 58.0 | nM | 352.39 | COc1ccc2nnn(CC(=O)N[C@@H](C)c3ccc(C)cc3)c(=O)c2c1 | Homo sapiens | CHEMBL4742408 | cell membrane format |
| CHEMBL4781729 |  |
Ki | = | 63.0 | nM | 336.4 | Cc1ccc([C@H](C)NC(=O)Cn2nnc3ccccc3c2=O)c(C)c1 | Homo sapiens | CHEMBL4742408 | cell membrane format |
| CHEMBL4789791 |  |
Ki | = | 72.0 | nM | 336.4 | Cc1ccc([C@H](C)NC(=O)Cn2nnc3c(C)cccc3c2=O)cc1 | Homo sapiens | CHEMBL4742408 | cell membrane format |
| CHEMBL4791752 |  |
Ki | = | 77.0 | nM | 358.35 | Cc1ccc([C@H](C)NC(=O)Cn2nnc3ccc(F)cc3c2=O)c(F)c1 | Homo sapiens | CHEMBL4742408 | cell membrane format |
| CHEMBL4797410 |  |
Ki | = | 85.0 | nM | 354.39 | Cc1ccc([C@H](C)NC(=O)Cn2nnc3c(F)cc(C)cc3c2=O)cc1 | Homo sapiens | CHEMBL4742408 | cell membrane format |
| CHEMBL4798933 |  |
Ki | = | 92.0 | nM | 336.4 | Cc1ccc([C@H](C)NC(=O)Cn2nnc3cccc(C)c3c2=O)cc1 | Homo sapiens | CHEMBL4742408 | cell membrane format |
| CHEMBL4780121 |  |
Ki | = | 93.0 | nM | 428.32 | C[C@H](NC(=O)Cn1nnc2ccc(F)cc2c1=O)c1ccc(OC(F)(F)F)cc1F | Homo sapiens | CHEMBL4742408 | cell membrane format |
| CHEMBL4797857 |  |
Ki | = | 106.0 | nM | 394.33 | C[C@H](NC(=O)Cn1nnc2ccc(F)cc2c1=O)c1ccc(C(F)(F)F)cc1 | Homo sapiens | CHEMBL4742408 | cell membrane format |
| CHEMBL4787761 |  |
Ki | = | 110.0 | nM | 356.81 | Cc1ccc([C@H](C)NC(=O)Cn2nnc3c(Cl)cccc3c2=O)cc1 | Homo sapiens | CHEMBL4742408 | cell membrane format |
| CHEMBL4794046 |  |
Ki | = | 115.0 | nM | 406.36 | COc1ccc2nnn(CC(=O)N[C@@H](C)c3ccc(C(F)(F)F)cc3)c(=O)c2c1 | Homo sapiens | CHEMBL4742408 | cell membrane format |
| CHEMBL4779773 |  |
Ki | = | 119.0 | nM | 392.34 | C[C@H](NC(=O)Cn1nnc2ccccc2c1=O)c1ccc(OC(F)(F)F)cc1 | Homo sapiens | CHEMBL4742408 | cell membrane format |