Q16739 | CEGT_HUMAN | Ceramide glucosyltransferase (UGCG)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF13506 | Glyco_transf_21 - Glycosyl transferase family 21 | 106~278 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5415209 |  |
IC50 | = | 0.9 | nM | 439.46 | Cc1nnc(-c2ccc(-c3c(F)c(F)cc4c3C(=O)N([C@H](C3CC3)C(C)(C)O)C4)cc2)o1 | Homo sapiens | CHEMBL5359305 | cell-based format |
| CHEMBL1911817 |  |
IC50 | = | 1.0 | nM | 577.0 | CN1CCN(C(=O)[C@@H](COCc2ccccc2)NC(=O)c2cccnc2Oc2ccc(C(F)(F)F)cc2Cl)CC1 | Homo sapiens | CHEMBL1912402 | single protein format |
| CHEMBL5290844 |  |
IC50 | = | 1.0 | nM | 404.87 | O=C(N1CCN2CCC1CC2)n1nc(-c2ccc(F)c(Cl)c2)c2c1COCC2 | Homo sapiens | CHEMBL5225965 | single protein format |
| CHEMBL2163821 |  |
IC50 | = | 2.0 | nM | 499.44 | CN1CCN(C(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C2(c3ccc(Cl)cc3Cl)CC2)CC1 | Homo sapiens | CHEMBL2167350 | single protein format |
| CHEMBL1911678 |  |
IC50 | = | 2.0 | nM | 418.58 | CCCCCCCCC(=O)N[C@@H](CN1CCCC1)[C@H](O)c1ccc2c(c1)OCCO2 | Homo sapiens | CHEMBL1912403 | cell-based format |
| CHEMBL1911679 |  |
IC50 | = | 2.0 | nM | 404.55 | CCCCCCCC(=O)N[C@@H](CN1CCCC1)[C@H](O)c1ccc2c(c1)OCCO2 | Homo sapiens | CHEMBL1912403 | cell-based format |
| CHEMBL1911816 |  |
IC50 | = | 2.0 | nM | 523.03 | Cc1cc(Cl)ccc1Oc1ncccc1C(=O)N[C@H](COCc1ccccc1)C(=O)N1CCN(C)CC1 | Homo sapiens | CHEMBL1912402 | single protein format |
| CHEMBL1911815 |  |
IC50 | = | 2.0 | nM | 543.45 | CN1CCN(C(=O)[C@@H](COCc2ccccc2)NC(=O)c2cccnc2Oc2ccc(Cl)cc2Cl)CC1 | Homo sapiens | CHEMBL1912402 | single protein format |
| CHEMBL2163825 |  |
IC50 | = | 2.0 | nM | 555.33 | NC1C[C@H]2CC[C@@H](C1)N2C(=O)[C@H](Cc1ccc(Cl)cc1Cl)NC(=O)C1(c2ccc(Cl)cc2Cl)CC1 | Homo sapiens | CHEMBL2167349 | cell-based format |
| CHEMBL5411678 |  |
IC50 | = | 2.1 | nM | 421.47 | Cc1nnc(-c2ccc(-c3cc(F)cc4c3C(=O)N([C@H](C3CC3)C(C)(C)O)C4)cc2)o1 | Homo sapiens | CHEMBL5359305 | cell-based format |
| CHEMBL3354637 |  |
IC50 | = | 2.5 | nM | 433.52 | OC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccccc2)c(F)c1 | Homo sapiens | CHEMBL3384689 | single protein format |
| CHEMBL5425600 |  |
IC50 | = | 2.6 | nM | 421.47 | Cc1nnc(-c2ccc(-c3c(F)ccc4c3C(=O)N([C@H](C3CC3)C(C)(C)O)C4)cc2)o1 | Homo sapiens | CHEMBL5359305 | cell-based format |
| CHEMBL3354024 |  |
IC50 | = | 3.0 | nM | 463.57 | OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc2ccc3cccc4ccc1c2c34 | Homo sapiens | CHEMBL3384689 | single protein format |
| CHEMBL3354022 |  |
IC50 | = | 3.0 | nM | 389.49 | OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc2ccccc2c1 | Homo sapiens | CHEMBL3384689 | single protein format |
| CHEMBL2163833 |  |
IC50 | = | 3.0 | nM | 494.85 | CN1CCN(C(=O)[C@H](Cc2ccc(Cl)cc2)NC(=O)C2(c3ccc(Cl)cc3Cl)CC2)CC1 | Homo sapiens | CHEMBL2167349 | cell-based format |
| CHEMBL2163823 |  |
IC50 | = | 3.0 | nM | 539.3 | NC1CCN(C(=O)[C@H](Cc2ccc(Br)cc2)NC(=O)C2(c3ccc(Cl)cc3Cl)CC2)CC1 | Homo sapiens | CHEMBL2167350 | single protein format |
| CHEMBL3354037 |  |
IC50 | = | 3.0 | nM | 463.57 | OC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc2ccc3cccc4ccc1c2c34 | Homo sapiens | CHEMBL3384689 | single protein format |
| CHEMBL3354035 |  |
IC50 | = | 3.0 | nM | 389.49 | OC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc2ccccc2c1 | Homo sapiens | CHEMBL3384689 | single protein format |
| CHEMBL3354634 |  |
IC50 | = | 3.0 | nM | 483.53 | OC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccccc2)cc1C(F)(F)F | Homo sapiens | CHEMBL3384689 | single protein format |
| CHEMBL1911814 |  |
IC50 | = | 3.0 | nM | 561.44 | CN1CCN(C(=O)[C@@H](COCc2ccccc2)NC(=O)c2cc(F)cnc2Oc2ccc(Cl)cc2Cl)CC1 | Homo sapiens | CHEMBL1912402 | single protein format |