Q16647 | PTGIS_HUMAN | Prostacyclin synthase (PTGIS)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00067 | p450 - Cytochrome P450 | 269~491 |
3D structures mapped by conservation among orthologs
[ Domain: "Cytochrome P450" // p450 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL353356 |  |
IC50 | < | 1000.0 | nM | 429.49 | CC(C)(Oc1ccccc1F)C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 | Homo sapiens | CHEMBL768446 | assay format |
| CHEMBL161518 |  |
IC50 | < | 1000.0 | nM | 456.5 | CC(C)(Oc1ccccc1[N+](=O)[O-])C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 | Homo sapiens | CHEMBL768446 | assay format |
| CHEMBL159859 |  |
IC50 | < | 1000.0 | nM | 490.39 | CC(C)(Oc1ccc(Br)cc1)C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 | Homo sapiens | CHEMBL768446 | assay format |