Q16644 | MAPK3_HUMAN | MAP kinase-activated protein kinase 3 (MAPKAPK3)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 47~304 |
3D structures mapped by conservation among orthologs
[ Domain: "Protein kinase" // Pkinase_Tyr ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL1231206 |  |
IC50 | = | 53.0 | nM | 374.47 | Cc1ccc(-c2ccc3c(ccc4sc5c(c43)NC[C@@H](C)NC5=O)n2)cn1 | Homo sapiens | CHEMBL5210309 | single protein format |
| CHEMBL226403 |  |
IC50 | = | 210.0 | nM | 340.39 | O=C1NCCc2[nH]c(-c3ccnc(-c4cnc5ccccc5c4)c3)cc21 | Homo sapiens | CHEMBL904790 | single protein format |
| CHEMBL3263640 |  |
IC50 | = | 213.0 | nM | 589.7 | Cc1c(NC(=O)c2ccc(C(C)(C)C)cc2)cccc1-c1nc(Nc2ccc(C(=O)N3CCOCC3)cc2)c2nc[nH]c2n1 | Homo sapiens | CHEMBL3270965 | single protein format |
| CHEMBL388566 |  |
IC50 | = | 660.0 | nM | 289.34 | O=C1NCCc2[nH]c(-c3ccnc(-c4ccccc4)c3)cc21 | Homo sapiens | CHEMBL904790 | single protein format |