Q16552 | IL17_HUMAN | Interleukin-17A (IL17A)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF06083 | IL17 - Interleukin-17 | 70~148 |
3D structures mapped by conservation among orthologs
[ Domain: "Cystine-knot cytokines" // IL17 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4876088 |  |
IC50 | = | 10.1 | nM | 568.51 | O=C(N[C@H](c1cn2ncc(CN3C[C@@H](C(F)(F)F)NC3=O)cc2n1)C1CCC(F)(F)CC1)c1nonc1C1CC1 | Homo sapiens | CHEMBL4831440 | cell-based format |
| CHEMBL4866932 |  |
IC50 | = | 10.1 | nM | 596.44 | O=C(N[C@H](c1cn2ncc(CN3C[C@@H](C(F)(F)F)NC3=O)cc2n1)C1CCC(F)(F)CC1)c1nonc1C(F)(F)F | Homo sapiens | CHEMBL4831440 | cell-based format |
| CHEMBL4860250 |  |
IC50 | = | 14.3 | nM | 570.52 | CC(C)c1nonc1C(=O)N[C@H](c1cn2ncc(CN3C[C@@H](C(F)(F)F)NC3=O)cc2n1)C1CCC(F)(F)CC1 | Homo sapiens | CHEMBL4831440 | cell-based format |
| CHEMBL5288854 |  |
IC50 | = | 221.0 | nM | 552.66 | CCS(=O)(=O)c1ccc(CC(=O)Nc2cnc3c(c2)CN(C[C@H]2CC[C@H](C(F)(F)F)CC2)[C@H]3C(C)C)nc1 | Homo sapiens | CHEMBL5223940 | single protein format |