Q16478 | GRIK5_HUMAN | Glutamate receptor ionotropic, kainate 5 (GRIK5)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00060 | Lig_chan - Ligand-gated ion channel | 545~815 | |
| PF01094 | ANF_receptor - Receptor family ligand binding region | 41~380 | |
| PF10613 | Lig_chan-Glu_bd - Ligated ion channel L-glutamate- and glycine-binding site | 415~528 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL121915 |  |
Ki | = | 0.24 | nM | 325.06 | N[C@@H](Cn1cc(I)c(=O)[nH]c1=O)C(=O)O | Homo sapiens | CHEMBL698076 | cell-based format |
| CHEMBL331644 |  |
Ki | = | 2.9 | nM | 279.05 | N[C@@H](Cn1nc(Br)c(=O)[nH]c1=O)C(=O)O | Homo sapiens | CHEMBL698076 | cell-based format |
| CHEMBL275040 |  |
Ki | = | 8.0 | nM | 213.23 | C=C(C)[C@H]1CN[C@H](C(=O)O)[C@H]1CC(=O)O | Homo sapiens | CHEMBL701557 | single protein format |
| CHEMBL333964 |  |
Ki | = | 9.1 | nM | 278.06 | N[C@@H](Cn1cc(Br)c(=O)[nH]c1=O)C(=O)O | Homo sapiens | CHEMBL698076 | cell-based format |
| CHEMBL121553 |  |
Ki | = | 19.8 | nM | 326.05 | N[C@@H](Cn1nc(I)c(=O)[nH]c1=O)C(=O)O | Homo sapiens | CHEMBL698076 | cell-based format |
| CHEMBL331696 |  |
Ki | = | 30.9 | nM | 234.6 | N[C@@H](Cn1nc(Cl)c(=O)[nH]c1=O)C(=O)O | Homo sapiens | CHEMBL698076 | cell-based format |
| CHEMBL121388 |  |
Ki | = | 57.1 | nM | 233.61 | N[C@@H](Cn1cc(Cl)c(=O)[nH]c1=O)C(=O)O | Homo sapiens | CHEMBL698076 | cell-based format |
| CHEMBL121191 |  |
Ki | = | 393.0 | nM | 244.16 | N[C@@H](Cn1cc([N+](=O)[O-])c(=O)[nH]c1=O)C(=O)O | Homo sapiens | CHEMBL698076 | cell-based format |
| CHEMBL575060 |  |
Ki | = | 750.0 | nM | 147.13 | N[C@@H](CCC(=O)O)C(=O)O | Homo sapiens | CHEMBL701557 | single protein format |