Q16445 | GBRA6_HUMAN | Gamma-aminobutyric acid receptor subunit alpha-6 (GABRA6)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF02931 | Neur_chan_LBD - Neurotransmitter-gated ion-channel ligand binding domain | 33~240 | |
| PF02932 | Neur_chan_memb - Neurotransmitter-gated ion-channel transmembrane region | 247~340 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL45198 |  |
Ki | = | 65.9 | nM | 386.48 | Cc1csc(-c2cc(-c3ccncc3)c3n(c2=O)CCCc2ccncc2-3)n1 | Homo sapiens | CHEMBL678892 | cell-based format |
| CHEMBL5275690 |  |
Ki | = | 75.0 | nM | 342.4 | CCOC(=O)c1nc(C)c2[nH]c3cc(OC)c(OC)cc3c2c1CC | Homo sapiens | CHEMBL5235572 | single protein format |
| CHEMBL5290579 |  |
Ki | = | 130.0 | nM | 328.37 | CCc1c(C(=O)OC)nc(C)c2[nH]c3cc(OC)c(OC)cc3c12 | Homo sapiens | CHEMBL5235572 | single protein format |
| CHEMBL5280240 |  |
Ki | = | 480.0 | nM | 314.34 | CCOC(=O)c1ncc2[nH]c3ccc(OC)cc3c2c1COC | Homo sapiens | CHEMBL5235572 | single protein format |