Q15761 | NPY5R_HUMAN | Neuropeptide Y receptor type 5 (NPY5R)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 - 7 transmembrane receptor (rhodopsin family) | 58~425 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL136974 |  |
IC50 | < | 0.1 | nM | 360.38 | Cc1nc(N2CCCCC2)c2[nH]c(-c3cccc(C(F)(F)F)c3)cc2n1 | Homo sapiens | CHEMBL857689 | single protein format |
| CHEMBL77589 |  |
IC50 | < | 0.1 | nM | 374.48 | CCC(Cc1ccccc1)N(C)C(=O)Nc1ccc(Oc2ccccc2)cc1 | Homo sapiens | CHEMBL872841 | single protein format |
| CHEMBL311552 |  |
IC50 | < | 0.1 | nM | 378.45 | CC(Cc1ccc(F)cc1)N(C)C(=O)Nc1ccc(Oc2ccccc2)cc1 | Homo sapiens | CHEMBL872841 | single protein format |
| CHEMBL335604 |  |
IC50 | < | 0.1 | nM | 328.37 | Cc1nc(N2CCCCC2)c2[nH]c(-c3ccc(F)c(F)c3)cc2n1 | Homo sapiens | CHEMBL857689 | single protein format |
| CHEMBL311506 |  |
IC50 | < | 0.1 | nM | 394.45 | C[C@H]([C@@H](O)c1ccccc1)N(C)C(=O)Nc1ccc(Oc2ccc(F)cc2)cc1 | Homo sapiens | CHEMBL872841 | single protein format |
| CHEMBL77770 |  |
IC50 | < | 0.1 | nM | 403.53 | CCN(c1ccccc1)c1ccc(NC(=O)N(C)[C@H](C)[C@@H](O)c2ccccc2)cc1 | Homo sapiens | CHEMBL872841 | single protein format |
| CHEMBL77276 |  |
IC50 | < | 0.1 | nM | 390.48 | COc1ccc(CC(C)N(C)C(=O)Nc2ccc(Oc3ccccc3)cc2)cc1 | Homo sapiens | CHEMBL872841 | single protein format |
| CHEMBL78040 |  |
IC50 | < | 0.1 | nM | 401.51 | CCn1c2ccccc2c2cc(NC(=O)N(C)[C@H](C)[C@@H](O)c3ccccc3)ccc21 | Homo sapiens | CHEMBL872841 | single protein format |
| CHEMBL312739 |  |
IC50 | < | 0.1 | nM | 374.48 | C[C@H]([C@@H](O)c1ccccc1)N(C)C(=O)Nc1ccc(Cc2ccccc2)cc1 | Homo sapiens | CHEMBL872841 | single protein format |
| CHEMBL137302 |  |
IC50 | < | 0.1 | nM | 346.36 | Cc1nc(N2CCCCC2)c2[nH]c(-c3cc(F)c(F)c(F)c3)cc2n1 | Homo sapiens | CHEMBL857689 | single protein format |
| CHEMBL424283 |  |
IC50 | < | 0.1 | nM | 326.83 | Cc1nc(N2CCCCC2)c2[nH]c(-c3cccc(Cl)c3)cc2n1 | Homo sapiens | CHEMBL857689 | single protein format |
| CHEMBL336711 |  |
IC50 | < | 0.1 | nM | 326.83 | Cc1nc(N2CCCCC2)c2[nH]c(-c3ccc(Cl)cc3)cc2n1 | Homo sapiens | CHEMBL857689 | single protein format |
| CHEMBL77776 |  |
IC50 | < | 0.1 | nM | 404.51 | Cc1ccc(Oc2ccc(NC(=O)N(C)[C@H](C)[C@@H](O)c3ccccc3)cc2)cc1C | Homo sapiens | CHEMBL872841 | single protein format |
| CHEMBL342438 |  |
IC50 | = | 0.2 | nM | 286.42 | CCCCCc1cc2[nH]c(C)nc(N3CCCCC3)c-2n1 | Homo sapiens | CHEMBL857689 | single protein format |
| CHEMBL492370 |  |
IC50 | = | 0.2 | nM | 454.38 | CS(=O)(=O)N1CC2(CCN(C(=O)Nc3ccc(Cl)c(Cl)c3)CC2)c2ccccc21 | Homo sapiens | CHEMBL1029921 | cell-based format |
| CHEMBL275841 |  |
IC50 | = | 0.23 | nM | 514.43 | O=C(Nc1ccc(Cl)c2ccccc12)C1CCN(C(=O)Cn2c(=O)sc3ccc(Cl)cc32)CC1 | Homo sapiens | CHEMBL750995 | cell-based format |
| CHEMBL135143 |  |
IC50 | = | 0.3 | nM | 332.41 | Cc1nc(N2CCCCC2)c2[nH]c(-c3cc4ccccc4o3)cc2n1 | Homo sapiens | CHEMBL857689 | single protein format |
| CHEMBL343817 |  |
IC50 | = | 0.3 | nM | 310.38 | Cc1nc(N2CCCCC2)c2[nH]c(-c3cccc(F)c3)cc2n1 | Homo sapiens | CHEMBL857689 | single protein format |
| CHEMBL138379 |  |
IC50 | = | 0.3 | nM | 310.38 | Cc1nc(N2CCCCC2)c2[nH]c(-c3ccc(F)cc3)cc2n1 | Homo sapiens | CHEMBL857689 | single protein format |
| CHEMBL137378 |  |
IC50 | = | 0.4 | nM | 328.37 | Cc1nc(N2CCCCC2)c2[nH]c(-c3cc(F)cc(F)c3)cc2n1 | Homo sapiens | CHEMBL857689 | single protein format |