Q15722 | LT4R1_HUMAN | Leukotriene B4 receptor 1 (LTB4R)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 - 7 transmembrane receptor (rhodopsin family) | 35~285 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL355401 |  |
IC50 | < | 0.1 | nM | 539.67 | CCCc1c(OCCCOc2ccc(C(=O)N3CCCC3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2 | Homo sapiens | CHEMBL709306 | single protein format |
| CHEMBL422388 |  |
IC50 | = | 0.1 | nM | 527.66 | CCCc1c(OCCCOc2ccc(C(=O)NC(C)C)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2 | Homo sapiens | CHEMBL709306 | single protein format |
| CHEMBL167350 |  |
IC50 | = | 0.15 | nM | 513.63 | CCCc1c(OCCCOc2ccc(C(=O)N(C)C)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2 | Homo sapiens | CHEMBL709306 | single protein format |
| CHEMBL167804 |  |
IC50 | = | 0.85 | nM | 499.6 | CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2 | Homo sapiens | CHEMBL709306 | single protein format |
| CHEMBL137759 |  |
IC50 | = | 1.0 | nM | 405.45 | O=C(O)CCCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1 | Homo sapiens | CHEMBL704375 | cell membrane format |
| CHEMBL419948 |  |
IC50 | = | 1.3 | nM | 539.67 | CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1O[C@H](CCC(=O)O)CC2 | Homo sapiens | CHEMBL709304 | single protein format |
| CHEMBL328492 |  |
IC50 | = | 1.5 | nM | 539.67 | CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1OC(CCC(=O)O)CC2 | Homo sapiens | CHEMBL709304 | single protein format |
| CHEMBL65061 |  |
IC50 | = | 1.9 | nM | 336.47 | CCCCC/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(=O)O | Homo sapiens | CHEMBL706534 | single protein format |
| CHEMBL137074 |  |
IC50 | = | 2.0 | nM | 453.92 | CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2Cl)n1)C(=O)O | Homo sapiens | CHEMBL704375 | cell membrane format |
| CHEMBL137336 |  |
IC50 | = | 2.0 | nM | 405.49 | COc1cccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)c1 | Homo sapiens | CHEMBL704375 | cell membrane format |
| CHEMBL136991 |  |
IC50 | = | 2.0 | nM | 376.46 | Nc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1 | Homo sapiens | CHEMBL704375 | cell membrane format |
| CHEMBL294987 |  |
IC50 | = | 2.9 | nM | 444.52 | CCCc1c(OCCCOc2cc(O)c(OC)cc2CC)ccc2c1OC(C(=O)O)CC2 | Homo sapiens | CHEMBL709312 | single protein format |
| CHEMBL137504 |  |
IC50 | = | 3.0 | nM | 361.44 | O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1 | Homo sapiens | CHEMBL704375 | cell membrane format |
| CHEMBL99099 |  |
IC50 | = | 3.2 | nM | 537.68 | CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CC2CC2)ccc2c1OC(C(=O)O)CC2 | Homo sapiens | CHEMBL708407 | single protein format |
| CHEMBL88337 |  |
IC50 | = | 4.0 | nM | 548.54 | CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O | Homo sapiens | CHEMBL709304 | single protein format |
| CHEMBL137581 |  |
IC50 | = | 4.0 | nM | 375.47 | CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O | Homo sapiens | CHEMBL704375 | cell membrane format |
| CHEMBL344230 |  |
IC50 | = | 4.0 | nM | 393.46 | CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2F)n1)C(=O)O | Homo sapiens | CHEMBL704375 | cell membrane format |
| CHEMBL137531 |  |
IC50 | = | 4.0 | nM | 405.49 | COc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1 | Homo sapiens | CHEMBL704375 | cell membrane format |
| CHEMBL89326 |  |
IC50 | = | 4.0 | nM | 455.6 | COc1cc(C(=O)N(C(C)C)C(C)C)ccc1OCCCCCOc1ccc(C(=N)N)cc1 | Homo sapiens | CHEMBL706922 | single protein format |
| CHEMBL416277 |  |
IC50 | = | 4.2 | nM | 458.55 | CCCc1c(OCCCOc2cc(O)c(OCC)cc2CC)ccc2c1OC(C(=O)O)CC2 | Homo sapiens | CHEMBL709312 | single protein format |