Q15392 | DHC24_HUMAN | Delta(24)-sterol reductase (DHCR24)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01565 | FAD_binding_4 - FAD binding domain | 111~202 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4164183 |  |
IC50 | = | 0.1 | nM | 332.53 | C[C@H](CO)[C@H]1CC[C@H]2C3=CC[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C | Homo sapiens | CHEMBL4134393 | cell-based format |
| CHEMBL352837 |  |
IC50 | = | 0.7 | nM | 401.64 | C[C@H](CCC(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C | Homo sapiens | CHEMBL4134393 | cell-based format |
| CHEMBL4174848 |  |
IC50 | = | 2.5 | nM | 332.53 | C[C@H](CO)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C | Homo sapiens | CHEMBL4134393 | cell-based format |
| CHEMBL4170755 |  |
IC50 | = | 2.9 | nM | 547.57 | C[C@H](/C=C/c1cc[n+](C)cc1)[C@H]1CC[C@H]2C3=CC[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C.[I-] | Homo sapiens | CHEMBL4134393 | cell-based format |
| CHEMBL4164005 |  |
IC50 | = | 3.3 | nM | 374.57 | CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC=C3[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)CO)CC[C@@H]32)C1 | Homo sapiens | CHEMBL4134393 | cell-based format |
| CHEMBL4167637 |  |
IC50 | = | 4.2 | nM | 402.58 | CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC=C3[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)COC=O)CC[C@@H]32)C1 | Homo sapiens | CHEMBL4134393 | cell-based format |
| CHEMBL4159728 |  |
IC50 | = | 5.5 | nM | 459.67 | CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC=C3[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)COC(=O)CN(C)C)CC[C@@H]32)C1 | Homo sapiens | CHEMBL4134393 | cell-based format |
| CHEMBL4164428 |  |
IC50 | = | 6.3 | nM | 442.64 | C/C=C/C(=O)OC[C@@H](C)[C@H]1CC[C@H]2C3=CC[C@H]4C[C@@H](OC(C)=O)CC[C@]4(C)[C@H]3CC[C@]12C | Homo sapiens | CHEMBL4134393 | cell-based format |
| CHEMBL4167452 |  |
IC50 | = | 198.0 | nM | 373.58 | CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC=C3[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)CN)CC[C@@H]32)C1 | Homo sapiens | CHEMBL4134393 | cell-based format |
| CHEMBL4172305 |  |
IC50 | = | 203.0 | nM | 456.67 | C/C=C(\C)C(=O)OC[C@@H](C)[C@H]1CC[C@H]2C3=CC[C@H]4C[C@@H](OC(C)=O)CC[C@]4(C)[C@H]3CC[C@]12C | Homo sapiens | CHEMBL4134393 | cell-based format |
| CHEMBL4173086 |  |
IC50 | = | 805.0 | nM | 417.59 | CONC(=O)[C@@H](C)[C@H]1CC[C@H]2C3=CC[C@H]4C[C@@H](OC(C)=O)CC[C@]4(C)[C@H]3CC[C@]12C | Homo sapiens | CHEMBL4134393 | cell-based format |
| CHEMBL4162816 |  |
IC50 | = | 823.0 | nM | 401.59 | CNC(=O)[C@@H](C)[C@H]1CC[C@H]2C3=CC[C@H]4C[C@@H](OC(C)=O)CC[C@]4(C)[C@H]3CC[C@]12C | Homo sapiens | CHEMBL4134393 | cell-based format |