Q15077 | P2RY6_HUMAN | P2Y purinoceptor 6 (P2RY6)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 | 44–300 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL1321988 |  |
IC50 | = | 37.0 | nM | 472.69 | S=C=Nc1cccc(NC(=S)NCCCCNC(=S)Nc2cccc(N=C=S)c2)c1 | Homo sapiens | CHEMBL5224962 | cell-based format |
| CHEMBL5272895 |  |
IC50 | = | 100.0 | nM | 296.42 | S=C=Nc1ccc(CCc2ccc(N=C=S)cc2)cc1 | Homo sapiens | CHEMBL5257758 | single protein format |
| CHEMBL4877204 |  |
IC50 | = | 155.0 | nM | 458.66 | S=C=Nc1ccc(NC(=S)NCCCNC(=S)Nc2ccc(N=C=S)cc2)cc1 | Homo sapiens | CHEMBL5385280 | single protein format |
| CHEMBL5274312 |  |
IC50 | = | 461.0 | nM | 383.44 | CC[Si](C#Cc1cccc2c1OC(C(F)(F)F)C([N+](=O)[O-])=C2)(CC)CC | Homo sapiens | CHEMBL5224961 | cell-based format |