Q14831 | GRM7_HUMAN | Metabotropic glutamate receptor 7 (GRM7)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00003 | 7tm_3 | 584–844 | |
| PF01094 | ANF_receptor | 78–484 | |
| PF07562 | NCD3G | 518–569 |
3D structures mapped by conservation among orthologs
[ Domain: "Periplasmic binding protein-like I" // ANF_receptor_2nd_1 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4176971 |  |
IC50 | = | 710.0 | nM | 408.34 | COc1ccc(C(=O)Nc2cc(OC(F)(F)F)ccc2-n2cncn2)cc1OC | Homo sapiens | CHEMBL5106323 | assay format |
| CHEMBL5202961 |  |
IC50 | = | 819.0 | nM | 480.4 | COc1cc(OCC(=O)Nc2cc(OC(F)(F)F)ccc2-n2cncn2)ccc1OC1COC1 | Homo sapiens | CHEMBL5106323 | assay format |
| CHEMBL5190992 |  |
IC50 | = | 830.0 | nM | 401.79 | COc1cc(-c2noc(-c3cc(Cl)ccc3-n3cncn3)n2)cc(F)c1OC | Homo sapiens | CHEMBL5106323 | assay format |
| CHEMBL5171986 |  |
IC50 | = | 860.0 | nM | 419.78 | COc1cc(F)c(-c2noc(-c3cc(Cl)ccc3-n3cncn3)n2)c(F)c1OC | Homo sapiens | CHEMBL5106323 | assay format |